[HTML][HTML] A prospective study of LINE-1DNA methylation and development of adiposity in school-age children

W Perng, M Mora-Plazas, C Marín, LS Rozek… - PLoS …, 2013 - journals.plos.org
Background Repetitive element DNA methylation is related to prominent obesity-related
chronic diseases including cancer and cardiovascular disease; yet, little is known of its …

[HTML][HTML] DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

FOL Vehmeijer, LK Küpers, GC Sharp, LA Salas… - Genome medicine, 2020 - Springer
Background DNA methylation has been shown to be associated with adiposity in adulthood.
However, whether similar DNA methylation patterns are associated with childhood and …

[HTML][HTML] LINE-1 methylation in visceral adipose tissue of severely obese individuals is associated with metabolic syndrome status and related phenotypes

V Turcot, A Tchernof, Y Deshaies, L Pérusse… - Clinical …, 2012 - Springer
Background Epigenetic mechanisms may be involved in the regulation of genes found to be
differentially expressed in the visceral adipose tissue (VAT) of severely obese subjects with …

[HTML][HTML] The relationship between body mass index, obesity, and LINE-1 methylation: a cross-sectional study on women from Southern Italy

A Maugeri, M Barchitta, R Magnano San Lio… - Disease …, 2021 - hindawi.com
Uncovering the relationship between body mass index (BMI) and DNA methylation could be
useful to understand molecular mechanisms underpinning the effects of obesity. Here, we …

Neonatal bloodspot DNA methylation patterns are associated with childhood weight status in the Healthy Families Project

J Kochmanski, JM Goodrich, KE Peterson… - Pediatric …, 2019 - nature.com
Background This study measured longitudinal DNA methylation dynamics at growth-related
genes during childhood, and then tested whether DNA methylation at various stages of …

[HTML][HTML] DNA methylation patterns in cord blood DNA and body size in childhood

CL Relton, A Groom, B St. Pourcain, AE Sayers… - PloS one, 2012 - journals.plos.org
Background Epigenetic markings acquired in early life may have phenotypic consequences
later in development through their role in transcriptional regulation with relevance to the …

No effect of weight loss on LINE‐1 methylation levels in peripheral blood leukocytes from postmenopausal overweight women

C Duggan, L Xiao, MB Terry, A McTiernan - Obesity, 2014 - Wiley Online Library
Objectives Obesity and weight‐loss are associated with methylation patterns in specific
genes, but their effect on Long Interspersed Nuclear Elements (LINE‐1) methylation, a …

DNA methylation of miRNA coding sequences putatively associated with childhood obesity

ML Mansego, M Garcia‐Lacarte, FI Milagro… - Pediatric …, 2017 - Wiley Online Library
Background Epigenetic mechanisms may be involved in obesity onset and its
consequences. The aim of the present study was to evaluate whether DNA methylation …

LINE-1 methylation is positively associated with healthier lifestyle but inversely related to body fat mass in healthy young individuals

JL Marques-Rocha, FI Milagro, ML Mansego… - Epigenetics, 2016 - Taylor & Francis
With the goal of investigating if epigenetic biomarkers from white blood cells (WBC) are
associated with dietary, anthropometric, metabolic, inflammatory and oxidative stress …

Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

RC Huang, PE Melton, MA Burton, LJ Beilin… - Epigenetics, 2022 - Taylor & Francis
Epigenetics links perinatal influences with later obesity. We identifed differentially
methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity …