Objective Experimental animal models have been used to investigate the formation,
development, and progression of abdominal aortic aneurysms (AAAs) for decades. New …

Introduction Abdominal aortic aneurysm (AAA) is a condition that has considerable
socioeconomic impact and an eventual rupture is associated with high mortality and …

Abdominal aortic aneurysm is a common degenerative disorder associated with sudden
death due to aortic rupture. Current therapy is limited to open surgical repair of the aorta or …

Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic
aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of …

Human abdominal aortic aneurysm (AAA) pathophysiology is not yet completely understood.
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …

Abdominal aortic aneurysm (AAA) is a prevalent and potentially life threatening disease.
Many animal models have been developed to simulate the natural history of the disease or …

Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

Abdominal aortic aneurysm (AAA) rupture is an important cause of death in older adults. In
clinical practice, the most established predictor of AAA rupture is maximum AAA diameter …

Background: Many studies have been performed in order to model abdominal aortic
aneurysm (AAA) in an experimental animal, most commonly in small laboratory animals. In …

Many mouse models of abdominal aortic aneurysms have been developed that use a
diverse array of methods for producing the disease, including genetic manipulation and …