Infertility is a complex disorder with multiple genetic and environmental causes. Although
some specific mutations have been identified, other factors responsible for sperm defects …

Male infertility is a common and complex problem affecting 1 in 20 men. Despite voluminous
research in this field, in many cases, the underlying causes are unknown. Epigenetic factors …

Epigenetic modifications characterized by DNA methylation, histone modifications, and
chromatin remodeling are important regulators in a number of biological processes …

Infertility affects approximately 15% of the couples wanting to conceive. In 30− 40% of the
cases the aetiology of male infertility remains unknown and is called idiopathic male …

Infertility is an often devastating diagnosis encountered by around one in six couples who
are trying to conceive. Moving away from the long-held belief that infertility is primarily a …

While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …

OBJECTIVE: To provide a link between epigenetics and male subfertility at the DNA, histone-
protamine, and RNA levels and its consequences on fertilization and embryo development …

The most common cause of male infertility is idiopathic. Fresh insights based on genetic and
molecular analysis of the human genome permit classification of formerly unexplained …

Male infertility is a complex condition with a strong genetic and epigenetic background. This
review discusses the importance of genetic and epigenetic factors in the pathophysiology of …

Although male infertility is currently diagnosed when abnormal sperm parameters are found,
the poor predictive ability of sperm parameters on natural fecundity and medically assisted …