A pooled analysis of three double-blind, randomized trials comparing clarithromycin (500
mg twice daily, n= 317) with either cefuroxime axetil (500 mg twice daily), cefaclor (500 mg …

1990). Although this may limit the number of patients eligible for study entry, it would ensure
that only patients with more severe exacerbations were included. Other symptoms and signs …

ACUTE RESPIRATORY INFECTIONS comprise one of the largest segments of clinical
problems encountered by the primary care physician. Respiratory tract infections are to a …

Background Acute bronchitis is one of the most common illnesses treated in the primary care
setting. Most patients are treated with antibiotics, despite the fact that acute bronchitis is …

Objectives: To assess the effect of a tailored professional intervention, including academic
detailing, on antibiotic prescribing for acute cough. Methods: In a cluster-randomized …

Editor—Farrell and Hall seem to have misunderstood the importance of the Swiss trials of
heroin on prescription for addicts. 1 The call for a clinical trial of heroin versus methadone is …

WE KNOW a lot more about acute bronchitis than we did a decade ago, mostly because of
work by family physicians who have been dissatisfied with current treatment options. The …

PURPOSE We hypothesized that antibiotic overuse for acute cough illness (ACI) is in part
due to a mismatch between patients' expectations and the natural history of ACI. METHODS …

The etiologic agents responsible for acute exacerbations of respiratory symptoms seen in
chronic bronchitis vary and include viral and bacterial infections and airborne irritants …

We have read with interest the meta-analysis by SIEMPOS et al.[1] evaluating the use of
different antibiotics for exacerbations of chronic bronchitis. We are puzzled by the criteria …