Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

S Moran, C Arribas, M Esteller - Epigenomics, 2016 - Taylor & Francis
Aim: DNA methylation is the best known epigenetic mark. Cancer and other pathologies
show an altered DNA methylome. However, delivering complete DNA methylation maps is …

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

J Sandoval, H Heyn, S Moran, J Serra-Musach… - Epigenetics, 2011 - Taylor & Francis
DNA methylation is the most studied epigenetic mark and CpG methylation is central to
many biological processes and human diseases. Since cancer has highlighted the …

Genome-scale DNA methylation analysis

SD Fouse, RP Nagarajan, JF Costello - Epigenomics, 2010 - Taylor & Francis
The haploid human genome contains approximately 29 million CpGs that exist in a
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …

[HTML][HTML] A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome …

C Clark, P Palta, CJ Joyce, C Scott, E Grundberg… - PloS one, 2012 - journals.plos.org
DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …

Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip

C Thirlwell, M Eymard, A Feber, A Teschendorff… - Methods, 2010 - Elsevier
Aberrant DNA methylation of promoter and other genomic regions can lead to changes in
gene expression, such as over-expression of oncogenes and the silencing of tumour …

Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets

JM Ordway, JA Bedell, RW Citek, A Nunberg… - …, 2006 - academic.oup.com
Using a unique microarray platform for cytosine methylation profiling, the DNA methylation
landscape of the human genome was monitored at more than 21 000 sites, including 79% of …

An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform

F Marabita, M Almgren, ME Lindholm, S Ruhrmann… - Epigenetics, 2013 - Taylor & Francis
The proper identification of differentially methylated CpGs is central in most epigenetic
studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA …

Complete Pipeline for Infinium® Human Methylation 450K BeadChip Data Processing Using Subset Quantile Normalization for Accurate DNA Methylation Estimation

N Touleimat, J Tost - Epigenomics, 2012 - Taylor & Francis
Background: Huge progress has been made in the development of array-or sequencing-
based technologies for DNA methylation analysis. The Illumina Infinium® Human …

Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome

FV Jacinto, E Ballestar, M Esteller - Biotechniques, 2008 - Taylor & Francis
One of the most challenging projects in the field of epigenetics is the generation of detailed
functional maps of DNA methylation in different cell and tissue types in normal and disease …

Genome-Wide Dna Methylation Profiling Using Infinium® Assay

M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
Aims: Bisulfite sequence analysis of individual CpG sites within genomic DNA is a powerful
approach for methylation analysis in the genome. The major limitation of bisulfite-based …