In this study, we assessed the relationships between the structure and estrogenicity of
flavonoid derivatives. We evaluated estrogenicity via yeast transactivation assays, E-screen …

Phytoestrogens are naturally occurring nonsteroidal phenolic plant compounds that, due to
their molecular structure and size, resemble vertebrate steroids estrogens. This review is …

Soy isoflavones have been studied extensively for estrogenic and antiestrogenic properties.
Other flavonoids, found in fruits, vegetables, tea and wine, have been much less tested for …

Background Estrogen receptors (ER) α and β are found in both women and men in many
tissues, where they have different functions, including having roles in cell proliferation and …

Isoflavonoids are a class of secondary metabolites, which comprise amongst others the
subclasses of isoflavones, isoflavans, pterocarpans and coumestans. Isoflavonoids are …

Although deoxybenzoins are intermediates in the synthesis of isoflavones, their estrogenic
activity has not been investigated. Eleven deoxybenzoins were synthesized and their …

Estrogens are steroid hormones exhibiting a broad range of physiological activities, which
are important in the homeostatic regulation of many cellular and biochemical events …

Isoflavones are the most potent estrogenic compounds in red clover extracts. Standardized
extracts have been discussed as an alternative for hormone replacement therapy. Variation …

In the search for estrogen receptor (ER) modulators, a series of prenylflavonoids were found
to be widely distributed amongst tonic herbal medicines and to possess estrogen‐like …

Resveratrol (RSV) is classified as a phytoestrogen due to its ability to interact with estrogen
receptors (ERs). We assessed structure–activity relationships of RSV and the analogs 4, 4 …