The weak estrogen-like properties of isoflavonoids were discovered over 50 y ago. In recent
years, the overall effects of the isoflavones in soy on human health have been the subject of …

Cancer is the world's devastating disease, and breast cancer is the most common reason for
the death of women worldwide. Many synthetic drugs and medications are provided with …

Licorice root contains chemically diverse compounds that exhibit estrogenic effects in vitro
and in vivo. The chalcone isoliquiritigenin (ISL) is a component of licorice extract exhibiting …

During recent years we have seen a paradigm shift in our understanding of oestrogen
action. This is mainly due to the discovery of a second oestrogen receptor,(ER) β, which is …

Erythrina poeppigiana is a medicinal plant which is widely used in Asia, Latin America, and
Africa in traditional remedies for gynecological complications and maladies. In continuation …

Non-prenylated isoflavone aglycones are known to have phyto-estrogenic properties and
act as agonistic ligands on ERα and ERβ due to their structural resemblance to 17β …

Objectives: Resveratrol (RSVL) is an edible phytoestrogen with multifaceted health benefits
that may originate from binding to the estrogen receptors. Despite its structural similarity to …

Isoflavonoids possess enormous potential for human health with potential impact on heart
disease and cancer, and some display striking affinities for steroid receptors. Synthesized …

Wedelolactone, a plant coumestan, was shown to act as anti-cancer agent for breast and
prostate carcinomas in vitro and in vivo targeting multiple cellular proteins including …

The estrogen receptors (ERs) ERα and ERβ mediate the actions of endogenous estrogens
as well as those of botanical estrogens (BEs) present in plants. BEs are ingested in the diet …