Epigenetic programming and fetal metabolic programming

Z Zhu, F Cao, X Li - Frontiers in endocrinology, 2019 - frontiersin.org
Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

Paternal epigenetic programming: evolving metabolic disease risk

SSJ Hur, JE Cropley, CM Suter - Journal of molecular …, 2017 - jme.bioscientifica.com
Parental health or exposures can affect the lifetime health outcomes of offspring,
independently of inherited genotypes. Such 'epigenetic'effects occur over a broad range of …

Early life nutrition, epigenetics and programming of later life disease

MH Vickers - Nutrients, 2014 - mdpi.com
The global pandemic of obesity and type 2 diabetes is often causally linked to marked
changes in diet and lifestyle; namely marked increases in dietary intakes of high energy …

Metabolic disease programming: from mitochondria to epigenetics, glucocorticoid signalling and beyond

LF Grilo, C Tocantins, MS Diniz… - European journal of …, 2021 - Wiley Online Library
Embryonic and foetal development are critical periods of development in which several
environmental cues determine health and disease in adulthood. Maternal conditions and an …

Maternal environment and the reproductive function of the offspring

C Dupont, AG Cordier, C Junien, B Mandon-Pepin… - Theriogenology, 2012 - Elsevier
Fetal programming of metabolic diseases is now a well established concept. The scope of
the Developmental Origins of Health and Disease has, however, widened and led to the …

Epigenetics and DOHaD: from basics to birth and beyond

T Bianco-Miotto, JM Craig, YP Gasser… - … origins of health and …, 2017 - cambridge.org
Developmental origins of health and disease (DOHaD) is the study of how the early life
environment can impact the risk of chronic diseases from childhood to adulthood and the …

[HTML][HTML] Nutrition, epigenetics, and diseases

H Jang, C Serra - Clinical nutrition research, 2014 - ncbi.nlm.nih.gov
Increasing epidemiological evidence suggests that maternal nutrition and environmental
exposure early in development play an important role in susceptibility to disease in later life …

Placental contribution to nutritional programming of health and diseases: epigenetics and sexual dimorphism

A Tarrade, P Panchenko, C Junien… - Journal of …, 2015 - journals.biologists.com
The recent and rapid worldwide increase in non-communicable diseases challenges the
assumption that genetic factors are the primary contributors to such diseases. A new concept …

Epigenetics as a driver of developmental origins of health and disease: did we forget the fathers?

A Soubry - Bioessays, 2018 - Wiley Online Library
What are the effects of our environment on human development and the next generation?
Numerous studies have provided ample evidence that a healthy environment and lifestyle of …

Epigenetics in the uterine environment: how maternal diet and ART may influence the epigenome in the offspring with long-term health consequences

I Peral-Sanchez, B Hojeij, DA Ojeda… - Genes, 2021 - mdpi.com
The societal burden of non-communicable disease is closely linked with environmental
exposures and lifestyle behaviours, including the adherence to a poor maternal diet from the …