Perinatal maternal undernutrition programs the offspring hypothalamo–pituitary–adrenal (HPA) axis
J Lesage, N Sebaai, M Leonhardt, I Dutriez-Casteloot… - Stress, 2006 - Taylor & Francis
There is now compelling evidence, coming both from animal and human studies that an
early exposure to undernutrition is frequently associated with low birth weight and programs …
early exposure to undernutrition is frequently associated with low birth weight and programs …
Perinatal environment and its influences on metabolic programming of offspring
KLK Tamashiro, TH Moran - Physiology & behavior, 2010 - Elsevier
The intrauterine environment supports the development and health of offspring.
Perturbations to this environment can have detrimental effects on the fetus that have …
Perturbations to this environment can have detrimental effects on the fetus that have …
Incorporating epigenetic mechanisms to advance fetal programming theories
Decades of fetal programming research indicates that we may be able to map the origins of
many physical, psychological, and medical variations and morbidities before the birth of the …
many physical, psychological, and medical variations and morbidities before the birth of the …
Impact of prenatal stress on neuroendocrine programming
O Viltart, CCA Vanbesien-Mailliot - The Scientific World Journal, 2007 - Wiley Online Library
Since life emerged on the Earth, the development of efficient strategies to cope with sudden
and/or permanent changes of the environment has been virtually the unique goal pursued …
and/or permanent changes of the environment has been virtually the unique goal pursued …
[HTML][HTML] A common cause for a common phenotype: the gatekeeper hypothesis in fetal programming
S McMullen, SC Langley-Evans, L Gambling, C Lang… - Medical hypotheses, 2012 - Elsevier
Sub-optimal nutrition during pregnancy has been shown to have long-term effects on the
health of offspring in both humans and animals. The most common outcomes of such …
health of offspring in both humans and animals. The most common outcomes of such …
[HTML][HTML] Epigenetic origins of metabolic disease: the impact of the maternal condition to the offspring epigenome and later health consequences
It has long been established that an adverse maternal condition impacts on the developing
fetus and predisposes the offspring to develop metabolic and cardiovascular disease in later …
fetus and predisposes the offspring to develop metabolic and cardiovascular disease in later …
Paternal programming of offspring cardiometabolic diseases in later life
J Li, O Tsuprykov, X Yang, B Hocher - Journal of hypertension, 2016 - journals.lww.com
Early–intrauterine–environmental factors are linked to the development of cardiovascular
disease in later life. Traditionally, these factors are considered to be maternal factors such as …
disease in later life. Traditionally, these factors are considered to be maternal factors such as …
[HTML][HTML] Development, epigenetics and metabolic programming
KM Godfrey, P Costello, K Lillycrop - Nestle Nutrition Institute …, 2016 - ncbi.nlm.nih.gov
It is now widely recognised that the environment in early life can have important effects on
human growth and development, including the “programming” of far reaching effects on the …
human growth and development, including the “programming” of far reaching effects on the …
Impact of oxidative stress in fetal programming
LP Thompson, Y Al-Hasan - Journal of pregnancy, 2012 - Wiley Online Library
Intrauterine stress induces increased risk of adult disease through fetal programming
mechanisms. Oxidative stress can be generated by several conditions, such as, prenatal …
mechanisms. Oxidative stress can be generated by several conditions, such as, prenatal …
Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects
A Thapar, G Harold, F Rice, XJ Ge, J Boivin… - BMC Medical Research …, 2007 - Springer
Background There is much evidence to suggest that risk for common clinical disorders
begins in foetal life. Exposure to environmental risk factors however is often not random …
begins in foetal life. Exposure to environmental risk factors however is often not random …