Iron acquisition in the human fungal pathogen Cryptococcus neoformans
Highlights•C. neoformans possesses high-affinity and low-affinity iron uptake systems.•The
reductive high-affinity iron uptake system is required for virulence.•The regulation of iron …
reductive high-affinity iron uptake system is required for virulence.•The regulation of iron …
A Transcriptional Regulatory Map of Iron Homeostasis Reveals a New Control Circuit for Capsule Formation in Cryptococcus neoformans
Transcriptional Regulatory Map of Iron Homeostasis Reveals a New Control Circuit for
Capsule Formation in Cryptococcus neoformans | Genetics | Oxford Academic Skip to Main …
Capsule Formation in Cryptococcus neoformans | Genetics | Oxford Academic Skip to Main …
An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans
JW Kronstad, G Hu, WH Jung - Trends in microbiology, 2013 - cell.com
Vertebrate hosts actively sequester iron, and fungal and other pathogens must therefore
adapt to a severe limitation in iron availability to cause disease. Recent studies reveal that …
adapt to a severe limitation in iron availability to cause disease. Recent studies reveal that …
Iron and fungal pathogenesis: a case study with Cryptococcus neoformans
WH Jung, JW Kronstad - Cellular microbiology, 2008 - Wiley Online Library
The acquisition of iron from mammalian hosts is an important aspect of infection because
microbes must compete with the host for this nutrient and iron perception often regulates …
microbes must compete with the host for this nutrient and iron perception often regulates …
[HTML][HTML] Iron source preference and regulation of iron uptake in Cryptococcus neoformans
The level of available iron in the mammalian host is extremely low, and pathogenic microbes
must compete with host proteins such as transferrin for iron. Iron regulation of gene …
must compete with host proteins such as transferrin for iron. Iron regulation of gene …
Role of ferric reductases in iron acquisition and virulence in the fungal pathogen Cryptococcus neoformans
S Saikia, D Oliveira, G Hu, J Kronstad - Infection and immunity, 2014 - Am Soc Microbiol
Iron acquisition is critical for the ability of the pathogenic yeast Cryptococcus neoformans to
cause disease in vertebrate hosts. In particular, iron overload exacerbates cryptococcal …
cause disease in vertebrate hosts. In particular, iron overload exacerbates cryptococcal …
[HTML][HTML] The Homeostasis of Iron, Copper, and Zinc in Paracoccidioides Brasiliensis, Cryptococcus Neoformans Var. Grubii, and Cryptococcus Gattii: A Comparative …
Iron, copper, and zinc are essential for all living organisms. Moreover, the homeostasis of
these metals is vital to microorganisms during pathogenic interactions with a host. Most …
these metals is vital to microorganisms during pathogenic interactions with a host. Most …
A human fungal pathogen Cryptococcus neoformans expresses three distinct iron permease homologs.
Iron plays a key role in host-pathogen interactions. Microbial pathogens require iron for
survival and virulence, whereas mammalian hosts sequester and withhold iron as a means …
survival and virulence, whereas mammalian hosts sequester and withhold iron as a means …
Role of Ferroxidases in Iron Uptake and Virulence of Cryptococcus neoformans
WH Jung, G Hu, W Kuo, JW Kronstad - Eukaryotic Cell, 2009 - Am Soc Microbiol
Iron acquisition is a critical aspect of the virulence of many pathogenic microbes, and iron
limitation is an important defense mechanism for mammalian hosts. We are examining …
limitation is an important defense mechanism for mammalian hosts. We are examining …
Cryptococcus neoformans can utilize ferritin as an iron source
M Song, EJ Thak, HA Kang, JW Kronstad… - Medical …, 2022 - academic.oup.com
Ferritin, a major iron storage protein in vertebrates, supplies iron upon iron deficiency.
Ferritin is also found extracellularly, and acts as an iron carrier and a contributor to the …
Ferritin is also found extracellularly, and acts as an iron carrier and a contributor to the …
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