[HTML][HTML] The onset of germ cell migration in the mouse embryo

R Anderson, TK Copeland, H Schöler… - Mechanisms of …, 2000 - Elsevier
Mouse primordial germ cells (PGCs) are specified between embryonic day 6.5 (E6. 5) and
E7. 5, when they have been visualized as an alkaline phosphatase-positive (AP+) cell …

[PDF][PDF] Time-lapse analysis of living mouse germ cell migration

KA Molyneaux, J Stallock, K Schaible, C Wylie - Developmental biology, 2001 - core.ac.uk
In mouse embryos, the primordial germ cells arise during gastrulation prior to, and distant
from, the prospective gonads. Observations of PGCs in culture, and in fixed sections, have …

Interactions between primordial germ cells play a role in their migration in mouse embryos

M Gomperts, M Garcia-Castro, C Wylie… - …, 1994 - journals.biologists.com
Primordial germ cells (PGCs) are the founder cell population of the gametes which form
during the sexually mature stage of the life cycle. In the mouse, they arise early in …

[HTML][HTML] Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis

K Hara, M Kanai-Azuma, M Uemura, H Shitara… - Developmental …, 2009 - Elsevier
During mouse gastrulation, primordial germ cells (PGCs) become clustered at the base of
the allantois and move caudally into the hindgut endoderm before entering the genital …

Genital ridges exert long-range effects on mouse primordial germ cell numbers and direction of migration in culture

I Godin, C Wylie, J Heasman - Development, 1990 - journals.biologists.com
The functional gametes of all vertebrates first arise in the early embryo as a migratory
population of cells, the primordial germ cells (PGCs). These migrate to, and colonise, the …

The origin and migration of primordial germ cells in the mouse

M Bendel–Stenzel, R Anderson, J Heasman… - Seminars in cell & …, 1998 - Elsevier
Primordial germ cells (PGCs) are the founders of the gametes. They migrate from their origin
to combine with the somatic component of the gonad. Progenitors in mice have been …

A light-and electron-microscopic study of primordial germ cells in the early mouse embryo

M Spiegelman, D Bennett - Development, 1973 - journals.biologists.com
The primordial germ cells (PGC's) of the early mouse embryo have been identified in semi-
thin and ultra-thin plastic sections on the combined bases of location and a distinctive set of …

Stage-specific tissue and cell interactions play key roles in mouse germ cell specification

T Yoshimizu, M Obinata, Y Matsui - Development, 2000 - journals.biologists.com
Primordial germ cells (PGCs) in mice have been recognized histologically as alkaline
phosphatase (AP) activity-positive cells at 7.2 days post coitum (dpc) in the extra-embryonic …

Origin, migration, and proliferation of human primordial germ cells

M De Felici - Oogenesis, 2013 - Springer
The first histological observations about the origin of the precursors of gametes termed
primordial germ cells (PGCs) in extragonadal regions and their subsequent migration into …

Primordial germ cells in the mouse embryo during gastrulation

M Ginsburg, MHL Snow, A McLaren - Development, 1990 - journals.biologists.com
With the aid of a whole-mount technique, we have detected a small cluster of alkaline
phosphatase (ALP)-positive cells in whole mounts of mid-primitive-streakstage embryos …