The present study applied T2-and diffusion-weighted magnetic resonance imaging to
examine if mild cerebral edema and subsequent brain swelling are implicated in the …

Acute mountain sickness is common among not acclimatized persons ascending to high
altitude; the underlying mechanism is unknown, but may be related to cerebral edema. Nine …

Acute mountain sickness (AMS) and high-altitude cerebral edema share common clinical
characteristics, suggesting cerebral swelling may be an important factor in the …

High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …

Individuals susceptible to high altitude pulmonary edema show altered pulmonary vascular
responses within minutes of exposure to hypoxia. We hypothesized that a similar acute …

In a randomized, double-blind cross-over study 10 subjects were exposed to a simulated
altitude of 4500 m for 10 h after administration of placebo, acetozolamide (250 mg bid) or …

Context.—Because of its onset in generally remote environments, high-altitude cerebral
edema (HACE) has received little scientific attention. Understanding the pathophysiology …

Rapid ascent to high altitude commonly results in acute mountain sickness, and on occasion
potentially fatal high-altitude cerebral edema. The exact pathophysiological mechanisms …

Traditionally, scientists and clinicians have explored peripheral physiological responses to
acute hypoxia to explain the pathophysiological processes that lead to acute mountain …

The diagnosis, treatment and prevention of high altitude cerebral edema (HACE) are fairly
well established. The major unresolved issues are 1) the pathophysiology, 2) the individual …