Acute mountain sickness (AMS) is a neurological disorder that typically affects mountaineers
who ascend to high altitude. The symptoms have traditionally been ascribed to intracranial …

Acute mountain sickness (AMS) is a common condition occurring within hours of rapid
exposure to high altitude. Despite its frequent occurrence, the pathophysiological …

Objective The study was undertaken to determine whether normobaric hypoxia causes
elevated brain volume and intracranial pressure in individuals with symptoms consistent …

MR imaging of high-altitude cerebral edema shows reversible WM edema, especially in the
corpus callosum and subcortical WM. Recent studies have revealed hemosiderin deposition …

Vasogenic edema in the corpus callosum is a characteristic finding in high-altitude cerebral
edema (HACE). Furthermore, microhemorrhages have been found at autopsies in brains of …

The present study combined molecular and neuroimaging techniques to examine if free
radical-mediated damage to barrier function in hypoxia would result in extracellular edema …

This review discusses the impact of recent publications on pathophysiologic concepts and
on practical aspects of acute mountain sickness (AMS). Magnetic resonance imaging …

To evaluate the pathogenetic role of cerebral blood flow (CBF) changes occurring before
and during the development of acute mountain sickness (AMS), peak mean middle cerebral …

The pathophysiology of acute mountain sickness (AMS) is unknown. One hypothesis is that
hypoxia induces biochemical changes that disrupt the blood-brain barrier (BBB) and …

Background High-altitude cerebral edema (HACE) is the severe type of acute mountain
sickness (AMS) and life threatening. A subclinical inflammation has been speculated, but the …