Integrins are heterodimeric cell surface receptors that mediate heterophilic cell-cell
interactions and interactions between cells and the extracellular matrix (Hynes RO. Cell 69 …

Integrins represent a superfamily of cell surface molecules that are important mediators of
cell-extracellular matrix interactions. Of the many known integrin subunit combinations, only …

A major hallmark of chronic kidney injury is fibrosis, which is characterized by increased
accumulation of extracellular matrix components that replace the damaged tissue. Normally …

The kidney develops from direct interactions between the ureteric bud and the metanephric
mesenchyme. The ureteric bud gives rise to the collecting system and the metanephric …

Nephrogenesis has been a long standing model of studies on epithelial-mesenchymal
interactions and differentiation. During nephrogenesis [reviewed in 1], the ingrowing ureter …

We have investigated the expression of integrin chains by human renal epithelial cells
during in vivo renal differentiation and in vitro cell culture on different extracellular matrices …

Integrins are a large family of transmembrane receptors for extracellular matrix (ECM)
molecules. They play a critical role in organ morphogenesis, physiology and pathology, as …

The extracellular matrix (ECM) exerts important effects on cell function that play a vital role in
such diverse processes as embryogenesis, wound healing, cancer metastasis, and …

The collagen-binding integrins α1β1 and α2β1 have profoundly different functions, yet they
are often co-expressed in epithelial cells. When both integrins are expressed in the same …

Integrin receptors and function on cultured glomerular endothelial cells. Integrin expression
and function on a cloned line of rat glomerular endothelial cells (GEndoC) were studied in …