Epithelial cell morphology and cytoskeletal organization are determined by interactions, with
both adjacent cells and the extracellular matrix, which are mediated by integrins and …

Cell adhesive interactions play important roles during many normal physiological processes
such as embryonic development and wound repair, and also during the progression of …

Adhesive interactions are crucial for the integrity and function of all cells and tissues. As one
of the major families of cell adhesion receptors, the integrins have been the focus of …

Integrin matrix receptors on glomerular epithelial cells (GEC) may play an important role in
adhesion of GEC to the glomerular basement membrane (GBM) and in the maintenance of …

In cultured human glomerular epithelial cells (HGEC), 25 mM glucose resulted in decreased
expression of α3-, α2-, and β1-integrins and increased expression of α5-and αvβ3-integrins …

Integrins receive signals from other receptors that lead to activation of ligand binding (inside-
out signaling) and matrix assembly. Upon binding ligands, they also activate intracellular …

The “integrin” terminology was applied in a 1987 review article (1) to describe a family of
structurally, immunochemically, and functionally related cell-surface heterodimeric …

Integrins are transmembrane receptors which bind extracellular matrix proteins and enable
not only cell adhesion and cytoskeleton organization but also transduction of critical signals …

Integrin α8β1 interacts with a variety of Arg-Gly-Asp (RGD)-containing ligands in the
extracellular matrix. Here, we examined the binding activities of α8β1 integrin toward a …

Recent mutations of most integrin genes in the mouse have provided new exciting insights
into the role of these integrins in cell—extracellular matrix interactions during development …