ZCCHC13-mediated induction of human liver cancer is associated with the modulation of DNA methylation and the AKT/ERK signaling pathway

Z Li, Z Li, L Wang, C Long, Z Zheng… - Journal of translational …, 2019 - Springer
Background Previous studies have shown that zinc-finger CCHC-type containing 13
(ZCCHC13) is located in an imprinted gene cluster in the X-inactivation centre, but few …

ZCCHC17 served as a predictive biomarker for prognosis and immunotherapy in Hepatocellular Carcinoma

F Liu, J Liang, P Long, L Zhu, W Hou, X Wu… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the common malignant tumors. The prognosis
and five-year survival rate of HCC are not promising due to tumor recurrence and …

[HTML][HTML] Identification and validation of the N6-methyladenosine RNA methylation regulator ZC3H13 as a novel prognostic marker and potential target for …

S Wu, G He, S Liu, Y Cao, C Geng… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract N6-methyladenosine (m6A) RNA methylation has been implicated in various
malignancies. This study aimed to identify prognostic signature based on m6A methylation …

ZCCHC9 promotes proliferation and invasion of lung cancer through regulating the JNK pathway

X Shi, B Jiang, H Liu, C Fan - Journal of Cellular Biochemistry, 2019 - Wiley Online Library
ZCCHC9 is a type of CCHC type zinc‐finger containing protein which was found to be
expressed in some tissues including brain and testicles in mice. Expression and function of …

ZC3H15 promotes glioblastoma progression through regulating EGFR stability

J Hou, M Xu, H Gu, D Pei, Y Liu, P Huang… - Cell death & …, 2022 - nature.com
Zinc finger CCCH-type containing 15 (ZC3H15), a highly conserved protein involved in
several cellular processes, which was responsible for tumorigenesis and may be a …

EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma

SB Gao, QF Zheng, B Xu, CB Pan, KL Li, Y Zhao… - Molecular Cancer …, 2014 - AACR
Alterations of polycomb group (PcG) genes directly modulate the trimethylation of histone H3
lysine 27 (H3K27me3) and may thus affect the epigenome of hepatocellular carcinoma …

HCV Core protein represses DKK3 expression via epigenetic silencing and activates the Wnt/β-catenin signaling pathway during the progression of HCC

X Wang, Y Zhou, C Wang, Y Zhao, Y Cheng… - Clinical and …, 2022 - Springer
The Wnt/β-catenin signaling pathway is frequently activated in hepatocellular carcinoma
(HCC). A number of studies have focused on the aberrant hypermethylation of the DKK …

ZCCHC14 regulates proliferation and invasion of non–small cell lung cancer through the MAPK‐P38 signalling pathway

X Shi, X Han, Y Cao, C Li, Y Cao - Journal of Cellular and …, 2021 - Wiley Online Library
ZCCHC14 is a CCHC‐type zinc finger protein which is expressed in tissues in human and
mouse. The function of ZCCHC14 in tumours remains unclear. In this research, we explored …

CXXC5 as an unmethylated CpG dinucleotide binding protein contributes to estrogen-mediated cellular proliferation

G Ayaz, N Razizadeh, P Yaşar, G Kars… - Scientific reports, 2020 - nature.com
Evidence suggests that the CXXC type zinc finger (ZF-CXXC) protein 5 (CXXC5) is a critical
regulator/integrator of various signaling pathways that include the estrogen (E2)-estrogen …

[HTML][HTML] Effect of CELSR3 on the cell cycle and apoptosis of hepatocellular carcinoma cells

Z Xie, Y Dang, H Wu, R He, J Ma, Z Peng… - Journal of …, 2020 - ncbi.nlm.nih.gov
Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3) has been reported in cancers
but its role and potential molecular mechanism in hepatocellular carcinoma (HCC) is …