To understand inflammation and immunity, we need to understand the biology of the
neutrophil. Whereas these cells can readily be extracted from peripheral blood, their short …

The outcome following injury can be healing, scarring or regeneration, all of which initiate
within a resolving inflammatory response. Regeneration, comprising the complete …

Neutrophils are highly motile phagocytic cells that play a critical role in the immune
response to infection. Zebrafish (Danio rerio) are increasingly used to study neutrophil …

Neutrophil chemotaxis to sites of inflammation is a critical process during normal immune
responses to tissue injury and infection and pathological immune responses leading to …

Neutrophilic inflammation is responsible for much of the tissue damage seen in many lung
diseases. For resolution of inflammation to occur, neutrophils must die by apoptosis …

Neutrophils are evolutionarily conserved innate immune cells playing pivotal roles in host
defense. Zebrafish models have contributed substantially to our understanding of neutrophil …

The precise control of neutrophil‐mediated inflammation is critical for both host defense and
the prevention of immunopathology. In vivo imaging studies in zebrafish, and more recently …

The current view of hematopoiesis considers leukocytes on a continuum with distinct
developmental origins, and which exert non-overlapping functions. However, there is less …

How neutrophils traffic during inflammation in vivo remains elusive. To visualize the origin
and fate of neutrophils during induction and resolution of inflammation, we established a …

The resolution of neutrophilic inflammation in the zebrafish can be visualized in vivo and
manipulated by a range of pharmacological mediators, demonstrating a role for neutrophil …