Extracellular vesicles and metastasis

SE Wang - Cold Spring Harbor perspectives in …, 2020 - perspectivesinmedicine.cshlp.org
Secretion of cell contents through extracellular vesicles (EVs), such as exosomes and
microvesicles, is a fundamental cell behavior. Compared with their normal counterparts …

The key role of extracellular vesicles in the metastatic process

H Zhao, A Achreja, E Iessi, M Logozzi, D Mizzoni… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Extracellular vesicles (EVs), including exosomes, have a key role in the paracrine
communication between organs and compartments. EVs shuttle virtually all types of …

[HTML][HTML] Extracellular vesicles in cancer: cell-to-cell mediators of metastasis

A Becker, BK Thakur, JM Weiss, HS Kim, H Peinado… - Cancer cell, 2016 - cell.com
Tumor-secreted extracellular vesicles (EVs) are critical mediators of intercellular
communication between tumor cells and stromal cells in local and distant …

The multifaceted role of extracellular vesicles in metastasis: Priming the soil for seeding

B dos Anjos Pultz… - … Journal of Cancer, 2017 - Wiley Online Library
Extracellular vesicles (EVs), including exosomes, play a key role in inter and intracellular
communication, promoting the proliferation and invasion of recipient cells to support tumor …

Extracellular vesicles in cancer diagnostics and therapeutics

A Shehzad, SU Islam, R Shahzad, S Khan… - Pharmacology & …, 2021 - Elsevier
Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

[HTML][HTML] Pathological and therapeutic significance of tumor-derived extracellular vesicles in cancer cell migration and metastasis

GL Liguori, V Kralj-Iglič - Cancers, 2023 - mdpi.com
Simple Summary Cancer metastasis accounts for almost 90% of cancer deaths worldwide.
The efficiency of current surgical, radiotherapeutic, and chemotherapeutic approaches is …

Extracellular vesicles in cancer—implications for future improvements in cancer care

R Xu, A Rai, M Chen, W Suwakulsiri… - Nature reviews Clinical …, 2018 - nature.com
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …

The role of extracellular vesicles in cancer microenvironment and metastasis: myths and challenges

F Lucien, HS Leong - Biochemical Society Transactions, 2019 - portlandpress.com
The concept of vesicles or cell debris released by cancer cells to promote metastasis is not
new, but the mechanisms used to currently ascribe their impact in metastasis are of intense …

[HTML][HTML] Delineating the role of extracellular vesicles in cancer metastasis: A comprehensive review

M Majood, S Rawat, S Mohanty - Frontiers in Immunology, 2022 - frontiersin.org
Extracellular vesicles (EVs) are subcellular messengers that aid in the formation and spread
of cancer by enabling tumor-stroma communication. EVs develop from the very porous …

Extracellular vesicles: important collaborators in cancer progression

S Sato, AM Weaver - Essays in biochemistry, 2018 - portlandpress.com
Extracellular vesicles (EVs) are membrane vesicles that are released from cells and mediate
cell–cell communication. EVs carry protein, lipid, and nucleic acid cargoes that interact with …