Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas

J Li, N Chen, X Gong - Molecular Medicine Reports, 2019 - spandidos-publications.com
RNA‑Sequencing and methylation data for hepatocellular carcinoma (HCC) were
downloaded from The Cancer Genome Atlas (TCGA). The aberrantly expressed methylation …

Aberrant promoter methylation profiles and association with survival in patients with hepatocellular carcinoma

D Zhong, H Cen - OncoTargets and therapy, 2017 - Taylor & Francis
The aim of this study was to investigate the prognostic and diagnostic value of genes with
promoter methylation in hepatocellular carcinoma (HCC) patients. On the basis of The …

[HTML][HTML] A prognostic model based on DNA methylation-related gene expression for predicting overall survival in hepatocellular carcinoma

J Luo, WC Zhu, QX Chen, CF Yang, BJ Huang… - Frontiers in …, 2024 - frontiersin.org
Background Hepatocellular carcinoma (HCC) continues to increase in morbidity and
mortality among all types of cancer. DNA methylation, an important epigenetic modification …

[HTML][HTML] An aberrant DNA methylation signature for predicting hepatocellular carcinoma

R Zhang, Y Li, H Yu, L Liu, C Zhu, S Zuo… - Annals of Translational …, 2020 - ncbi.nlm.nih.gov
Background By the time they are clinically diagnosed, patients with hepatocellular
carcinoma (HCC) are often at the advanced stage. DNA methylation has become a useful …

A novel DNA methylation-based model that effectively predicts prognosis in hepatocellular carcinoma

XY Hao, AQ Li, H Shi, TK Guo, YF Shen… - Bioscience …, 2021 - portlandpress.com
Purpose: To build a novel predictive model for hepatocellular carcinoma (HCC) patients
based on DNA methylation data. Methods: Four independent DNA methylation datasets for …

DNA methylation biomarkers for hepatocellular carcinoma

G Fan, Y Tu, C Chen, H Sun, C Wan, X Cai - Cancer cell international, 2018 - Springer
Background Aberrant methylation of DNA is a key driver of hepatocellular carcinoma (HCC).
In this study, we sought to integrate four cohorts profile datasets to identify such abnormally …

HDNA methylation data-based molecular subtype classification related to the prognosis of patients with hepatocellular carcinoma

H He, D Chen, S Cui, G Wu, H Piao, X Wang, P Ye… - BMC Medical …, 2020 - Springer
Background DNA methylation is a common chemical modification of DNA in the
carcinogenesis of hepatocellular carcinoma (HCC). Methods In this bioinformatics analysis …

A novel DNA methylation‐driver gene signature for long‐term survival prediction of hepatitis‐positive hepatocellular carcinoma patients

J Fu, W Qin, Q Tong, Z Li, Y Shao, Z Liu, C Liu… - Cancer …, 2022 - Wiley Online Library
Background Abnormal DNA methylation is one of the most general epigenetic modifications
in hepatocellular carcinoma (HCC). Recent research showed that DNA methylation was a …

Integrative analysis of DNA methylation and gene expression identify a six epigenetic driver signature for predicting prognosis in hepatocellular carcinoma

G Li, Z Ding, Y Wang, T Liu, W Chen… - Journal of cellular …, 2019 - Wiley Online Library
DNA methylation is a crucial regulator of gene transcription in the etiology and pathogenesis
of hepatocellular carcinoma (HCC). Thus, it is reasonable to identify DNA methylation …

[HTML][HTML] Aberrantly DNA methylated-differentially expressed genes and pathways in hepatocellular carcinoma

C Cai, W Wang, Z Tu - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Background: Methylation plays a significant role in the etiology and pathogenesis of
hepatocellular carcinoma (HCC). The aim of the present study is to identify aberrantly …