A comprehensive overview of Infinium HumanMethylation450 data processing

S Dedeurwaerder, M Defrance, M Bizet… - Briefings in …, 2014 - academic.oup.com
Infinium HumanMethylation450 beadarray is a popular technology to explore DNA
methylomes in health and disease, and there is a current explosion in the use of this …

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

MJ Aryee, AE Jaffe, H Corrada-Bravo… - …, 2014 - academic.oup.com
Abstract Motivation: The recently released Infinium HumanMethylation450 array (the
'450k'array) provides a high-throughput assay to quantify DNA methylation (DNAm) at∼ 450 …

Measuring the methylome in clinical samples: improved processing of the Infinium Human Methylation450 BeadChip Array

H Pan, L Chen, S Dogra, A Ling Teh, J Hao Tan… - Epigenetics, 2012 - Taylor & Francis
The Infinium Human Methylation450 BeadChip ArrayTM (Infinium 450K) is an important tool
for studying epigenetic patterns associated with disease. This array offers a high-throughput …

[HTML][HTML] Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data

TJ Morris, S Beck - Methods, 2015 - Elsevier
Abstract The Illumina HumanMethylation450 BeadChip has become a popular platform for
interrogating DNA methylation in epigenome-wide association studies (EWAS) and related …

[HTML][HTML] A framework for analyzing DNA methylation data from Illumina Infinium HumanMethylation450 BeadChip

Z Wang, XL Wu, Y Wang - BMC bioinformatics, 2018 - Springer
Background DNA methylation has been identified to be widely associated to complex
diseases. Among biological platforms to profile DNA methylation in human, the Illumina …

A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data

T Wang, W Guan, J Lin, N Boutaoui, G Canino, J Luo… - Epigenetics, 2015 - Taylor & Francis
DNA methylation plays an important role in disease etiology. The Illumina Infinium
HumanMethylation450 (450K) BeadChip is a widely used platform in large-scale …

A systematic assessment of normalization approaches for the Infinium 450K methylation platform

MC Wu, BR Joubert, P Kuan, SE Håberg, W Nystad… - Epigenetics, 2014 - Taylor & Francis
The Illumina Infinium HumanMethylation450 BeadChip has emerged as one of the most
popular platforms for genome wide profiling of DNA methylation. While the technology is …

missMethyl: an R package for analyzing data from Illumina's HumanMethylation450 platform

B Phipson, J Maksimovic, A Oshlack - Bioinformatics, 2015 - academic.oup.com
DNA methylation is one of the most commonly studied epigenetic modifications due to its
role in both disease and development. The Illumina HumanMethylation450 BeadChip is a …

Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray

S Moran, M Vizoso, A Martinez-Cardús, A Gomez… - epigenetics, 2014 - Taylor & Francis
A formalin-fixed paraffin-embedded (FFPE) sample usually yields highly degraded DNA,
which limits the use of techniques requiring high-quality DNA, such as Infinium Methylation …

[HTML][HTML] An evaluation of processing methods for HumanMethylation450 BeadChip data

J Liu, KD Siegmund - BMC genomics, 2016 - Springer
Abstract Background Illumina's HumanMethylation450 arrays provide the most cost-effective
means of high-throughput DNA methylation analysis. As with other types of microarray …