Objective To summarize the current evidence on the biomarkers associated with DNA
methylation in the screening and diagnosis of colorectal cancer (CRC). Methods A literature …

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

Colorectal cancer (CRC) is a leading cancer globally; therefore, early diagnosis and
surveillance of this cancer are of paramount importance. Current methods of CRC diagnosis …

Since genetic and epigenetic alterations influence the development of colorectal cancer
(CRC), huge potential lies in the use of DNA methylation as biomarkers to improve the …

Colorectal cancer (CRC) arises as a consequence of the accumulation of genetic and
epigenetic alterations in colonic epithelial cells during neoplastic transformation. Epigenetic …

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer (CRC) and
precursor lesions have been extensively studied. Different panels have been reported …

Colorectal cancer (CRC) arises from accumulated genetic and epigenetic alterations, which
provide the possibility to identify tumor-specific biomarkers by analyzing fecal DNA …

Purpose Methylated cell-free DNA in liquid biopsies are promising non-invasive biomarkers
for colorectal cancer (CRC). Optimal markers would have high sensitivity and specificity for …

OBJECTIVES: To improve colorectal cancer (CRC) survival and lower incidence rates,
colonoscopy and/or fecal immunochemical test screening are widely implemented. Although …

A large number of tumor-related methylated genes have been suggested to be of diagnostic
and prognostic values for CRC when analyzed in patients' stool samples; however, reported …