The role of DNA demethylation during development
A Weiss, H Cedar - Genes to Cells, 1997 - Wiley Online Library
The somatic genomic methylation pattern which plays a role in the suppression of basal
gene activity is established anew in each generation through developmentally regulated de …
gene activity is established anew in each generation through developmentally regulated de …
Notes on the role of dynamic DNA methylation in mammalian development
TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
It has been nearly 40 y since it was suggested that genomic methylation patterns could be
transmitted via maintenance methylation during S phase and might play a role in the …
transmitted via maintenance methylation during S phase and might play a role in the …
DNA methylation and embryogenesis
A Razin, H Cedar - DNA methylation: molecular biology and biological …, 1993 - Springer
A large number of studies have documented the methylation patterns of individual genes
and repeated sequences in different tissues of various mammalian species. This has …
and repeated sequences in different tissues of various mammalian species. This has …
DNA methylation in early mammalian development
D Jähner, R Jaenisch - DNA methylation: Biochemistry and biological …, 1984 - Springer
The genomic DNAs of vertebrates and many invertebrates contain 5-methylcytosine (5-
meCyt) as the only modified base (Table 10.1). Considerable interest in DNA methylation …
meCyt) as the only modified base (Table 10.1). Considerable interest in DNA methylation …
DNA methylation from embryo to adult
A Razin, T Kafri - Progress in nucleic acid research and molecular …, 1994 - Elsevier
Publisher Summary This chapter discusses the deoxyribonucleic acid (DNA) methylation
from embryo to adult. The existence of tissue-specific methylation patterns and the results of …
from embryo to adult. The existence of tissue-specific methylation patterns and the results of …
Hypomethylation of DNA in the regulation of gene expression
LA Chandler, PA Jones - The Molecular Biology of Cell Determination and …, 1988 - Springer
Cellular differentiation involves the activation of a specific set of genes as well as the
suppression of those genes associated with the differentiation of other cell types …
suppression of those genes associated with the differentiation of other cell types …
DNA methylation in eukaryotic cells
A Razin, H Cedar - International review of cytology, 1984 - Elsevier
Publisher Summary This chapter discusses DNA methylation in eukaryotic cells. DNA
methylation pattern undergoes discrete changes, especially during the process of …
methylation pattern undergoes discrete changes, especially during the process of …
DNA methylation and gene activity.
H Cedar - Cell, 1988 - europepmc.org
The above experiments support a relatively simple model to explain the role of DNA
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may …
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may …
Gene methylation patterns and expression
J Yisraeli, M Szyf - DNA methylation: biochemistry and biological …, 1984 - Springer
Three basic approaches have been employed in the study of the effect of DNA methylation
of particular genes on their expression. One approach uses chemicals that cause …
of particular genes on their expression. One approach uses chemicals that cause …
Mechanisms of DNA methylation and demethylation during mammalian development
N Veland, T Chen - Handbook of Epigenetics, 2017 - Elsevier
DNA methylation, the addition of a methyl group at the 5-position of cytosine (5-
methylcytosine, 5mC), is a major epigenetic modification in the genomes of many animals …
methylcytosine, 5mC), is a major epigenetic modification in the genomes of many animals …