Fifty children with idiopathic membranoproliferative glomerulonephritis (MPGN), aged 2–14
years at apparent onset, were monitored for the presence of C3 nephritic factor (C3 NeF) …

The development of membranoproliferative glomerulonephritis (MPGN) is associated with
uncontrolled activation of the complement alternative pathway. This dysregulation is related …

Membranoproliferative glomerulonephritis (MPGN), recognized since 1965, is now known to
have three forms, designated types I, II, and III. The types are similar in the frequency of …

One hundred patents diagnosed with hypocomplementaemic MPGN (C3< 40%) were
studied to determine the presence of C3 nephritic factor (C3NeF) and/or C4 nephritic factor …

Recent advances in our understanding of the disease pathology of membranoproliferative
glomerulonephritis has resulted in its re-classification as complement C3 glomerulopathy …

Serum levels of the C3 nephritic factor (C3NeF), an IgG autoantibody directed against the
C3bBb convertase of the alternative complement pathway, and of eight complement …

Membranoproliferative glomerulonephritis (MPGN) is a rare chronic kidney disease
associated with complement activation. Recent immunofluorescence-based classification …

Abstract Aim C3 glomerulonephritis (C3GN) is a recently described disease that is related to
membranoproliferative glomerulonephritis (MPGN). We retrospectively compared the …

Classical complement pathway activation in membranoprolifera-tive glomerulonephritis.
Levels of components of the classical and alternative complement pathways and the activity …

Membranoproliferative glomerulonephritis is an uncommon kidney disorder characterized
by mesangial cell proliferation and structural changes in glomerular capillary walls. It can be …