Identification and localization of polycystin, the PKD1 gene product.
L Geng, Y Segal, B Peissel, N Deng… - The Journal of …, 1996 - Am Soc Clin Investig
Polycystin, the product of autosomal dominant polycystic kidney disease (ADPKD) 1 gene
(PKD1) is the cardinal member of a novel class of proteins. As a first step towards …
(PKD1) is the cardinal member of a novel class of proteins. As a first step towards …
Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue
A second gene for autosomal dominant polycystic kidney disease (ADPKD), PKD2, has
been recently identified. Using antisera raised to the human PKD2 protein, polycystin-2, we …
been recently identified. Using antisera raised to the human PKD2 protein, polycystin-2, we …
Immunolocalization of polycystin in human tissues and cultured cells.
MD Griffin, VE Torres, JP Grande… - Proceedings of the …, 1996 - europepmc.org
The gene PKD I, which is mutated in type I autosomal dominant polycystic kidney disease
(ADPKD 1), encodes a large protein of novel structure and unknown function and …
(ADPKD 1), encodes a large protein of novel structure and unknown function and …
Characterization and cell distribution of polycystin, the product of autosomal dominant polycystic kidney disease gene 1
Background In a majority of cases, autosomal dominant polycystic kidney disease (ADPKD)
is caused by mutations within a putative open reading frame of the PKD1 gene. The …
is caused by mutations within a putative open reading frame of the PKD1 gene. The …
Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)
B Veldhuisen, L Spruit, HG Dauwerse… - European Journal of …, 1999 - nature.com
Abstract Autosomal Dominant Polycystic Kidney Disease (ADPKD), a common inherited
disease leading to progressive renal failure, can be caused by a mutation in either the PKD1 …
disease leading to progressive renal failure, can be caused by a mutation in either the PKD1 …
Cellular localization and tissue distribution of polycystin‐1
DJM Peters, A van de Wal, L Spruit… - The Journal of …, 1999 - Wiley Online Library
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of
fluid‐filled cysts in both kidneys, in addition to a variety of extra‐renal manifestations. The …
fluid‐filled cysts in both kidneys, in addition to a variety of extra‐renal manifestations. The …
Distribution and developmentally regulated expression of murine polycystin
L Geng, Y Segal, A Pavlova… - American Journal …, 1997 - journals.physiology.org
PKD1, the gene that is mutated in approximately 85% of autosomal dominant polycystic
kidney disease (ADPKD) cases in humans, has recently been identified (Eur. PKD …
kidney disease (ADPKD) cases in humans, has recently been identified (Eur. PKD …
Biochemical characterization of bona fide polycystin-1 in vitro and in vivo
The most common form of autosomal dominant polycystic kidney disease (PKD) results from
mutation of the PKD1 gene on chromosome 16p13. 3. The gene encodes a 14-kb …
mutation of the PKD1 gene on chromosome 16p13. 3. The gene encodes a 14-kb …
Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney.
Polycystic kidney disease 1 (PKD1) is the major locus of the common genetic disorder
autosomal dominant polycystic kidney disease. We have studied PKD1 mRNA, with an …
autosomal dominant polycystic kidney disease. We have studied PKD1 mRNA, with an …
Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains
R Sandford, B Sgotto, S Aparicio… - Human molecular …, 1997 - academic.oup.com
PKD1 is the major locus of the common genetic disorder autosomal dominant polycystic
kidney disease (ADPKD). Analysis of the predicted protein sequence of the human PKD1 …
kidney disease (ADPKD). Analysis of the predicted protein sequence of the human PKD1 …