DNA methylation is an epigenetic mark linking DNA sequence and transcription regulation,
and therefore plays an important role in phenotypic plasticity. The ideal whole genome …

DNA methylation is an epigenetic mark that has a crucial role in many biological processes.
To understand the functional consequences of DNA methylation on phenotypic plasticity, a …

Aims: To compare the performance of four sequence-based and one microarray methods for
DNA methylation profiling. Methods: DNA from two cell lines were profiled by reduced …

DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …

DNA methylation is a key component of mammalian gene regulation and the most classical
example of an epigenetic mark. DNA methylation patterns are mitotically heritable and …

DNA modifications, such as methylation and hydroxymethylation, are pivotal players in
modulating gene expression, genomic imprinting, X-chromosome inactivation, and silencing …

One of the most challenging projects in the field of epigenetics is the generation of detailed
functional maps of DNA methylation in different cell and tissue types in normal and disease …

The methylated DNA immunoprecipitation method (MeDIP) is a genome-wide, high-
resolution approach that detects DNA methylation with oligonucleotide tiling arrays or high …

DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …

Background DNA methylation contributes to the regulation of gene expression during
development and cellular differentiation. The recently developed Methylated DNA …