The pathogenesis of intracranial aneurysms remains complex and multifactorial. While
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …

Background Rupture is the most serious consequence of cerebral aneurysms, and its
likelihood depends on nonmodifiable and modifiable risk factors. Recent efforts have …

Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …

Intracranial aneurysms and associated subarachnoid hemorrhage (SAH) are predominant
cerebrovascular disorders that present a significant public health risk through high rates of …

BACKGROUND AND PURPOSE: Cerebral aneurysms are preferentially located at arterial
curvatures and bifurcations that are exposed to major hemodynamic forces, increasingly …

Many factors that are either blood-, wall-, or hemodynamics-borne have been associated
with the initiation, growth, and rupture of intracranial aneurysms. The distribution of cerebral …

Background Intracranial aneurysm (IA) is a disease of the vascular wall resulting in
abnormal enlargement of the vessel lumen. It is a common pathology with a prevalence of …

BACKGROUND: Recent evidence suggests a link between the magnitude and distribution of
hemodynamic factors and the formation and rupture of intracranial aneurysms. However …

Objective The detailed mechanisms of cerebral aneurysm evolution are poorly understood
but are important for objective aneurysm evaluation and improved patient management. The …

BACKGROUND AND PURPOSE: Aneurysm progression and rupture is thought to be
governed by progressive degradation and weakening of the wall in response to abnormal …