Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions
MK Skinner, C Guerrero-Bosagna - Bmc Genomics, 2014 - Springer
Background Previously a variety of environmental toxicants were found to promote the
epigenetic transgenerational inheritance of disease through differential DNA methylation …
epigenetic transgenerational inheritance of disease through differential DNA methylation …
Identification of genomic features in environmentally induced epigenetic transgenerational inherited sperm epimutations
C Guerrero-Bosagna, S Weeks, MK Skinner - PloS one, 2014 - journals.plos.org
A variety of environmental toxicants have been shown to induce the epigenetic
transgenerational inheritance of disease and phenotypic variation. The process involves …
transgenerational inheritance of disease and phenotypic variation. The process involves …
Genomic Clustering of differential DNA methylated regions (epimutations) associated with the epigenetic transgenerational inheritance of disease and phenotypic …
MM Haque, EE Nilsson, LB Holder, MK Skinner - BMC genomics, 2016 - Springer
Background A variety of environmental factors have been shown to promote the epigenetic
transgenerational inheritance of disease and phenotypic variation in numerous species …
transgenerational inheritance of disease and phenotypic variation in numerous species …
Generational comparisons (F1 versus F3) of vinclozolin induced epigenetic transgenerational inheritance of sperm differential DNA methylation regions (epimutations) …
D Beck, I Sadler-Riggleman… - Environmental …, 2017 - academic.oup.com
Environmentally induced epigenetic transgenerational inheritance of disease and
phenotypic variation has been shown to involve DNA methylation alterations in the germline …
phenotypic variation has been shown to involve DNA methylation alterations in the germline …
Environmentally induced epigenetic transgenerational inheritance of sperm epimutations promote genetic mutations
MK Skinner, C Guerrero-Bosagna, MM Haque - Epigenetics, 2015 - Taylor & Francis
A variety of environmental factors have been shown to induce the epigenetic
transgenerational inheritance of disease and phenotypic variation. This involves the …
transgenerational inheritance of disease and phenotypic variation. This involves the …
Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease
MK Skinner, M Ben Maamar, I Sadler-Riggleman… - Epigenetics & …, 2018 - Springer
Background Environmental toxicants such as DDT have been shown to induce the
epigenetic transgenerational inheritance of disease (eg, obesity) through the germline. The …
epigenetic transgenerational inheritance of disease (eg, obesity) through the germline. The …
[HTML][HTML] Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure
MB Maamar, E Nilsson, I Sadler-Riggleman… - Developmental …, 2019 - Elsevier
Epigenetic alterations in the germline can be triggered by a number of different
environmental factors from diet to toxicants. These environmentally induced germline …
environmental factors from diet to toxicants. These environmentally induced germline …
Epigenetic inheritance is unfaithful at intermediately methylated CpG sites
AD Hay, NJ Kessler, D Gebert, N Takahashi… - Nature …, 2023 - nature.com
DNA methylation at the CpG dinucleotide is considered a stable epigenetic mark due to its
presumed long-term inheritance through clonal expansion. Here, we perform high …
presumed long-term inheritance through clonal expansion. Here, we perform high …
Epigenome-wide association study for pesticide (Permethrin and DEET) induced DNA methylation epimutation biomarkers for specific transgenerational disease
JLM Thorson, D Beck, M Ben Maamar, EE Nilsson… - Environmental …, 2020 - Springer
Abstract Background Permethrin and N, N-diethyl-meta-toluamide (DEET) are the pesticides
and insect repellent most commonly used by humans. These pesticides have been shown to …
and insect repellent most commonly used by humans. These pesticides have been shown to …
Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations
M Manikkam, R Tracey, C Guerrero-Bosagna… - Reproductive …, 2012 - Elsevier
Environmental compounds are known to promote epigenetic transgenerational inheritance
of disease. The current study was designed to determine if a “pesticide mixture”(pesticide …
of disease. The current study was designed to determine if a “pesticide mixture”(pesticide …