The transcriptome profile of human embryonic stem cells as defined by SAGE
M Richards, SP Tan, JH Tan, WK Chan, A Bongso - Stem cells, 2004 - academic.oup.com
Human embryonic stem (ES) cell lines that have the ability to self‐renew and differentiate
into specific cell types have been established. The molecular mechanisms for self‐renewal …
into specific cell types have been established. The molecular mechanisms for self‐renewal …
Mechanisms of self-renewal in human embryonic stem cells
R Stewart, M Stojkovic, M Lako - European Journal of Cancer, 2006 - Elsevier
Embryonic stem cells (ESCs) are the pluripotent cell population derived from the inner cell
mass of pre-implantation embryos and are characterised by prolonged self-renewal and the …
mass of pre-implantation embryos and are characterised by prolonged self-renewal and the …
A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity
S Ruiz, AD Panopoulos, A Herrerías, KD Bissig, M Lutz… - Current Biology, 2011 - cell.com
Human embryonic stem (hES) cells show an atypical cell-cycle regulation characterized by a
high proliferation rate and a short G1 phase [1, 2]. In fact, a shortened G1 phase might …
high proliferation rate and a short G1 phase [1, 2]. In fact, a shortened G1 phase might …
Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells
M Pritsker, NR Ford, HT Jenq… - Proceedings of the …, 2006 - National Acad Sciences
Embryonic stem (ES) cells hold great promise for the future of medicine. To elucidate the
molecular mechanisms that control ES cell self-renewal and differentiation, a …
molecular mechanisms that control ES cell self-renewal and differentiation, a …
A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
We performed a genome-wide siRNA screen in mouse embryonic stem (ES) cells to identify
genes essential for self-renewal, and found 148 genes whose down-regulation caused …
genes essential for self-renewal, and found 148 genes whose down-regulation caused …
Multilineage differentiation from human embryonic stem cell lines
JS Odorico, DS Kaufman, JA Thomson - Stem cells, 2001 - academic.oup.com
Stem cells are unique cell populations with the ability to undergo both self-renewal and
differentiation. A wide variety of adult mammalian tissues harbors stem cells, yet “adult” stem …
differentiation. A wide variety of adult mammalian tissues harbors stem cells, yet “adult” stem …
Molecular mechanisms underlying pluripotency and self-renewal of embryonic stem cells
Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst.
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …
Embryonic stem cells
A Biswas, R Hutchins - Stem cells and development, 2007 - liebertpub.com
Stem cells are unique cell populations with the ability to choose between self-renewal and
differentiation. Embryonic stem (ES) cells have the ability to form any fully differentiated cell …
differentiation. Embryonic stem (ES) cells have the ability to form any fully differentiated cell …
Molecular ties between the cell cycle and differentiation in embryonic stem cells
VC Li, MW Kirschner - … of the National Academy of Sciences, 2014 - National Acad Sciences
Attainment of the differentiated state during the final stages of somatic cell differentiation is
closely tied to cell cycle progression. Much less is known about the role of the cell cycle at …
closely tied to cell cycle progression. Much less is known about the role of the cell cycle at …
Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells
T Enver, S Soneji, C Joshi, J Brown… - Human molecular …, 2005 - academic.oup.com
Human embryonic stem cell (HESC) lines vary in their characteristics and behaviour not only
because they are derived from genetically outbred populations, but also because they may …
because they are derived from genetically outbred populations, but also because they may …