Human embryonic stem (ES) cell lines that have the ability to self‐renew and differentiate
into specific cell types have been established. The molecular mechanisms for self‐renewal …

Embryonic stem cells (ESCs) are the pluripotent cell population derived from the inner cell
mass of pre-implantation embryos and are characterised by prolonged self-renewal and the …

Human embryonic stem (hES) cells show an atypical cell-cycle regulation characterized by a
high proliferation rate and a short G1 phase [1, 2]. In fact, a shortened G1 phase might …

Embryonic stem (ES) cells hold great promise for the future of medicine. To elucidate the
molecular mechanisms that control ES cell self-renewal and differentiation, a …

We performed a genome-wide siRNA screen in mouse embryonic stem (ES) cells to identify
genes essential for self-renewal, and found 148 genes whose down-regulation caused …

Stem cells are unique cell populations with the ability to undergo both self-renewal and
differentiation. A wide variety of adult mammalian tissues harbors stem cells, yet “adult” stem …

Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst.
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …

Stem cells are unique cell populations with the ability to choose between self-renewal and
differentiation. Embryonic stem (ES) cells have the ability to form any fully differentiated cell …

Attainment of the differentiated state during the final stages of somatic cell differentiation is
closely tied to cell cycle progression. Much less is known about the role of the cell cycle at …

Human embryonic stem cell (HESC) lines vary in their characteristics and behaviour not only
because they are derived from genetically outbred populations, but also because they may …