[HTML][HTML] Contribution of human embryonic stem cells to mouse blastocysts

D James, SA Noggle, T Swigut, AH Brivanlou - Developmental biology, 2006 - Elsevier
In addition to their potential for cell-based therapies in the treatment of disease and injury,
the broad developmental capacity of human embryonic stem cells (hESCs) offers potential …

Mouse ES cell culture system as a model of development

H Niwa - Development, growth & differentiation, 2010 - Wiley Online Library
Mouse embryonic stem (mES) cells are pluripotent stem cells derived from pre‐implantation
embryos. They are regarded as an essential tool for studying mouse development, as they …

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

NY Chia, YS Chan, B Feng, X Lu, YL Orlov, D Moreau… - Nature, 2010 - nature.com
The derivation of human ES cells (hESCs) from human blastocysts represents one of the
milestones in stem cell biology. The full potential of hESCs in research and clinical …

Defined conditions for propagation and manipulation of mouse embryonic stem cells

C Mulas, T Kalkan, F von Meyenn, HG Leitch… - …, 2019 - journals.biologists.com
The power of mouse embryonic stem (ES) cells to colonise the developing embryo has
revolutionised mammalian developmental genetics and stem cell research. This power is …

The transcriptional regulation of pluripotency

JC Yeo, HH Ng - Cell research, 2013 - nature.com
The defining features of embryonic stem cells (ESCs) are their self-renewing and pluripotent
capacities. Indeed, the ability to give rise into all cell types within the organism not only …

Human embryonic stem cell technology

JM Jones, JA Thomson - Seminars in reproductive medicine, 2000 - thieme-connect.com
Undifferentiated human embryonic stem (ES) cells can be cultured indefinitely and yet
maintain the potential to form almost every cell in the adult human body. Therefore ES cells …

Derivation and spontaneous differentiation of human embryonic stem cells

M Amit, J Itskovitz‐Eldor - Journal of anatomy, 2002 - Wiley Online Library
Embryonic stem (ES) cells are unique cells derived from the inner cell mass of the
mammalian blastocyst. These cells are immortal and pluripotent, retain their developmental …

Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state

CL Wei, T Miura, P Robson, SK Lim, XQ Xu… - Stem …, 2005 - academic.oup.com
Human embryonic stem cells (hESCs) are an important source of stem cells in regenerative
medicine, and much remains unknown about their molecular characteristics. To develop a …

Deconstructing stemness

H Mikkers, J Frisén - The EMBO journal, 2005 - embopress.org
Stem cells are unique in their capacity to self‐renew and generate differentiated progeny to
maintain tissues throughout life. A common molecular program for stem cells has remained …

[PDF][PDF] Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA-Seq analysis

F Tang, C Barbacioru, S Bao, C Lee, E Nordman… - Cell stem cell, 2010 - cell.com
During the transition from the inner cell mass (ICM) cells of blastocysts to pluripotent
embryonic stem cells (ESCs) in vitro, a normal developmental program is replaced in cells …