[PDF][PDF] Microevolution of serial clinical isolates of Cryptococcus neoformans var. grubii and C. gattii. mBio 8: e00166-17

Y Chen, RA Farrer, C Giamberardino, S Sakthikumar… - 2017 - dukespace.lib.duke.edu
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …

Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii

Y Chen, RA Farrer, C Giamberardino, S Sakthikumar… - MBio, 2017 - Am Soc Microbiol
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …

A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence

CA Morrow, IR Lee, EWL Chow, KL Ormerod… - MBio, 2012 - Am Soc Microbiol
The accumulation of genomic structural variation between closely related populations over
time can lead to reproductive isolation and speciation. The fungal pathogen Cryptococcus is …

Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts

CA D'souza, JW Kronstad, G Taylor, R Warren, M Yuen… - MBio, 2011 - Am Soc Microbiol
Cryptococcus gattii recently emerged as the causative agent of cryptococcosis in healthy
individuals in western North America, despite previous characterization of the fungus as a …

Multilocus sequence typing of serially collected isolates of Cryptococcus from HIV-infected patients in South Africa

M Van Wyk, NP Govender, TG Mitchell… - Journal of clinical …, 2014 - Am Soc Microbiol
Patients with cryptococcal meningitis in sub-Saharan Africa frequently relapse following
treatment. The natural history and etiology of these recurrent episodes warrant investigation …

Rising to the challenge of multiple Cryptococcus species and the diseases they cause

A Idnurm, X Lin - Fungal Genetics and Biology, 2015 - Elsevier
Cryptococcus neoformans and Cryptococcus gattii are well-studied basidiomyceteous
yeasts that are capable of causing disease in healthy and immunocompromised people. The …

[HTML][HTML] Advances in Cryptococcus genomics: insights into the evolution of pathogenesis

CA Cuomo, J Rhodes, CA Desjardins - Memórias do Instituto …, 2018 - SciELO Brasil
Cryptococcus species are the causative agents of cryptococcal meningitis, a significant
source of mortality in immunocompromised individuals. Initial work on the molecular …

Genetic diversity and microevolution in clinical Cryptococcus isolates from Cameroon

P Sephton-Clark, E Temfack, JL Tenor… - Medical …, 2023 - academic.oup.com
Cryptococcal meningitis is the second most common cause of death in people living with
HIV/AIDS, yet we have a limited understanding of how cryptococcal isolates change over the …

[HTML][HTML] Cryptococcus neoformans Genotypic Diversity and Disease Outcome among HIV Patients in Africa

K Kassaza, F Wasswa, K Nielsen, J Bazira - Journal of Fungi, 2022 - mdpi.com
Cryptococcal meningoencephalitis, a disease with poor patient outcomes, remains the most
prevalent invasive fungal infection worldwide, accounting for approximately 180,000 deaths …

Molecular Typing of the Cryptococcus neoformans/Cryptococcus gattii Species Complex

W Meyer, F Gilgado, P Ngamskulrungroj… - … human pathogen to …, 2010 - Wiley Online Library
A large number of molecular typing techniques have been applied over the years to
discriminate between individual isolates that had been indistinguishable using conventional …