Nutrition is a key environmental factor that is particularly involved in the pathogenesis and
progression of several polygenic, diet-related diseases. Nutrigenomics refers to the …

Dietary fat has a dual role in human physiology: a) it functions as a source of energy and
structural components for cells; b) it functions as a regulator of gene expression that impacts …

The last decade has provided evidence that major and minor dietary constituents can
regulate gene expression in a hormonally independent manner. Fatty acids, cholesterol, and …

Background The effect of dietary fats on human health and disease are likely mediated by
changes in gene expression. Several transcription factors have been shown to respond to …

Nutrigenomics employs high-throughput genomics technologies to unravel how nutrients
modulate gene and protein expression and ultimately influence cellular and organism …

The type and quantity of dietary fat ingested contributes to the onset and progression of
chronic diseases, such as diabetes and atherosclerosis. The liver plays a central role in …

▪ Abstract Apart from being an important macronutrient, dietary fat has recently gained much
prominence for its role in regulating gene expression. Polyunsaturated fatty acids (PUFAs) …

Extracellular signals are transmitted to intracellular targets through many signal-transduction
pathways. Each signaling pathway is composed of a network of interacting signaling …

▪ Abstract Dietary fat is an important macronutrient for the growth and development of all
organisms. In addition to its role as an energy source and its effects on membrane lipid …

Consumption of specific dietary fatty acids has been shown to influence risk and progression
of several chronic diseases, such as cardiovascular disease, obesity, cancer, and arthritis. In …