Background Previously, a role was demonstrated for transcription in the acquisition of DNA
methylation at imprinted control regions in oocytes. Definition of the oocyte DNA methylome …

DNA methylation occurs on cytosines, is catalyzed by DNA methyltransferases (DNMTs),
and is present at high levels in all vertebrates. DNA methylation plays essential roles in …

DNA methylation is evolutionarily conserved. Vertebrates exhibit high, widespread DNA
methylation whereas invertebrate genomes are less methylated, predominantly within gene …

Complex cytoplasmic nucleotide-sensing mechanisms can recognize foreign DNA based on
a lack of methylation and initiate an immune response to clear the infection. Zebrafish …

The segregation of eukaryotic genomes into euchromatin and heterochromatin represents a
fundamental and poorly understood process. Here, we demonstrate that genome-wide …

DNA methylation of transcription units (gene bodies) occurs in the genomes of many animal
and plant species. Phylogenetic persistence of gene body methylation implies biological …

Critical epigenetic regulation of primate embryogenesis entails DNA methylome changes.
Here we report genome-wide composition, patterning, and stage-specific dynamics of DNA …

Two techniques were used to analyze global genomic 5-methyl cytosine methylation at
CCGG sites of medaka embryo DNA. DNA was labeled by incorporation of microinjected …

Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …

DNA methylation, a well-studied epigenetic mark, is important for gene regulation in
adulthood and for development. Using genetic and epigenetic approaches, the present …