In a randomized, double-blind cross-over study 10 subjects were exposed to a simulated
altitude of 4500 m for 10 h after administration of placebo, acetozolamide (250 mg bid) or …

Background and Purpose—Acute mountain sickness (AMS) may be an early stage of high
altitude cerebral edema. If so, AMS could result from an alteration of dynamic autoregulation …

Objective: Based on recent findings of microhemorrhages (MHs) in the corpus callosum
(CC) in 3 individuals after nonfatal high-altitude cerebral edema (HACE), we hypothesized …

Abstract Wilson, Mark H., CHE Imray, AR Hargens. The headache of high altitude and
microgravity—similarities with clinical syndromes of cerebral venous hypertension. High Alt …

High-altitude cerebral edema (HACE) is a potentially fatal metabolic encephalopathy
associated with a time-dependent exposure to the hypobaric hypoxia of altitude. Symptoms …

High-altitude illnesses have profound consequences on the health of many unsuspecting
and otherwise healthy individuals who sojourn to high altitude for recreation and work. The …

The pathophysiology of acute mountain sickness and high-altitude cerebral edema, the
cerebral forms of high-altitude illness, remain uncertain and controversial. Persistently …

Introduction Headache is the most common complication associated with exposure to high
altitude, and can appear as an isolated high-altitude headache (HAH) or in conjunction with …

After ascent to high altitude (≥ 2500 m), the inability of the human body to adapt to the
hypobaric and hypoxia environment can induce tissue hypoxia, then a series of high altitude …

High-altitude cerebral edema (HACE) has been tentatively attributed to either cellular ion
pump failure from ATP depletion or high cerebral blood flow inducing high capillary …