Fighting infectious diseases, particularly viral infections, is a demanding task for human
health. Targeting the pathogens or targeting the host are different strategies, but with an …

Coronaviruses (CoVs) are a group of single stranded RNA viruses, of which some of them
such as SARS-CoV, MERS-CoV, and SARS-CoV-2 are associated with deadly worldwide …

Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The
current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore …

Melatonin may be a powerful auxiliary therapy in the prevention and treatment of viral
infections, such as coronavirus disease 2019 (COVID-19)[1]. Casually, the so-called 'super …

Melatonin, an endogenous indoleamine, is an antioxidant and anti-inflammatory molecule
widely distributed in the body. It efficiently regulates pro-inflammatory and anti-inflammatory …

There is a growing consensus that the antioxidant and anti-inflammatory properties of
melatonin are of great importance in preserving the body functions and homeostasis, with …

Numerous pharmaceutical drugs have been repurposed for use as treatments for COVID-19
disease. These drugs have not consistently demonstrated high efficacy in preventing or …

Coronaviruses (CoVs) are RNA viruses that cause infections of the respiratory,
gastrointestinal, and central nervous systems, among others. The pathological symptoms of …

The high mortality of deadly virus infectious diseases including SARS, MERS, COVID-19,
and avian flu is often caused by the uncontrolled innate immune response and destructive …

The fear of SARS-CoV-2 infection is due to its high mortality related to seasonal flu. To date,
few medicines have been developed to significantly reduce the mortality of the severe …