DNA methylation patterns provide insight into epigenetic regulation in the Pacific oyster (Crassostrea gigas)

MR Gavery, SB Roberts - BMC genomics, 2010 - Springer
Background DNA methylation is an epigenetic mechanism with important regulatory
functions in animals. While the mechanism itself is evolutionarily ancient, the distribution and …

DNA methylation in human epigenomes depends on local topology of CpG sites

C Lövkvist, IB Dodd, K Sneppen… - Nucleic acids …, 2016 - academic.oup.com
In vertebrates, methylation of cytosine at CpG sequences is implicated in stable and
heritable patterns of gene expression. The classical model for inheritance, in which …

DNA sequence explains seemingly disordered methylation levels in partially methylated domains of Mammalian genomes

D Gaidatzis, L Burger, R Murr, A Lerch… - PLoS …, 2014 - journals.plos.org
For the most part metazoan genomes are highly methylated and harbor only small regions
with low or absent methylation. In contrast, partially methylated domains (PMDs), recently …

The evolution of invertebrate gene body methylation

S Sarda, J Zeng, BG Hunt, SV Yi - Molecular biology and …, 2012 - academic.oup.com
DNA methylation of transcription units (gene bodies) occurs in the genomes of many animal
and plant species. Phylogenetic persistence of gene body methylation implies biological …

The methyl-CpG binding domain and the evolving role of DNA methylation in animals

B Hendrich, S Tweedie - TRENDS in Genetics, 2003 - cell.com
DNA methylation occurs in bacteria, fungi, plants and animals, however its role varies widely
among different organisms. Even within animal genomes, methylation patterns vary …

DNA methylation: old dog, new tricks?

CG Spruijt, M Vermeulen - Nature structural & molecular biology, 2014 - nature.com
DNA methylation is an epigenetic modification that is generally associated with repression of
transcription initiation at CpG-island promoters. Here we argue that, on the basis of recent …

Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum

NKE Schulz, CI Wagner, J Ebeling, G Raddatz… - Scientific reports, 2018 - nature.com
Epigenetic mechanisms, such as CpG DNA methylation enable phenotypic plasticity and
rapid adaptation to changing environments. CpG DNA methylation is established by DNA …

Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape

L Veselovska, SA Smallwood, H Saadeh, KR Stewart… - Genome biology, 2015 - Springer
Background Previously, a role was demonstrated for transcription in the acquisition of DNA
methylation at imprinted control regions in oocytes. Definition of the oocyte DNA methylome …

Signatures of DNA methylation across insects suggest reduced DNA methylation levels in Holometabola

P Provataris, K Meusemann, O Niehuis… - Genome biology and …, 2018 - academic.oup.com
It has been experimentally shown that DNA methylation is involved in the regulation of gene
expression and the silencing of transposable element activity in eukaryotes. The variable …

Collaboration between CpG sites is needed for stable somatic inheritance of DNA methylation states

JO Haerter, C Lövkvist, IB Dodd… - Nucleic acids …, 2014 - academic.oup.com
Inheritance of 5-methyl cytosine modification of CpG (CG/CG) DNA sequences is needed to
maintain early developmental decisions in vertebrates. The standard inheritance model …