Newly emerging therapies for neonatal seizures
RM Pressler, B Mangum - Seminars in Fetal and Neonatal Medicine, 2013 - Elsevier
The treatment of neonatal seizures has not changed significantly over the last 50 years
despite advances in antiepileptic drug (AED) development for older children and adults …
despite advances in antiepileptic drug (AED) development for older children and adults …
Neonatal seizures: controversies and challenges in translating new therapies from the lab to the isolette
KE Chapman, YH Raol… - European Journal of …, 2012 - Wiley Online Library
Neonatal seizures have unique properties that have proved challenging for both clinicians
and basic science researchers. Clinical therapies aimed at neonatal seizures have proven …
and basic science researchers. Clinical therapies aimed at neonatal seizures have proven …
Treatment of neonatal seizures
LGM van Rooij, L Hellström-Westas… - Seminars in Fetal and …, 2013 - Elsevier
Seizures occur more often during the neonatal period than at any other period of life. Precise
incidence is difficult to delineate and depends on study population and criteria used for …
incidence is difficult to delineate and depends on study population and criteria used for …
Clinical management of seizures in newborns: diagnosis and treatment
LGM van Rooij, MPH van den Broek, CMA Rademaker… - Pediatric Drugs, 2013 - Springer
Neonatal seizures can be classified as tonic, clonic, myoclonic, and subtle. A clinical
diagnosis is not easy as seizures are usually subtle in neonates. In the majority of newborn …
diagnosis is not easy as seizures are usually subtle in neonates. In the majority of newborn …
Off-label use of antiepileptic drugs for the treatment of neonatal seizures
FS Silverstein, DM Ferriero - Pediatric neurology, 2008 - Elsevier
Medically refractory neonatal seizures represent a major therapeutic challenge in neonatal
intensive care units. Conventional antiepileptic drugs demonstrate limited efficacy. Previous …
intensive care units. Conventional antiepileptic drugs demonstrate limited efficacy. Previous …
Pharmacotherapy for neonatal seizures: current knowledge and future perspectives
Seizures are the most common neurological emergencies in the neonatal period and are
associated with poor neurodevelopmental outcomes. Seizures affect up to five per 1000 …
associated with poor neurodevelopmental outcomes. Seizures affect up to five per 1000 …
Pharmacological treatment of neonatal seizures: a systematic review
LA Slaughter, AD Patel… - Journal of child …, 2013 - journals.sagepub.com
Pharmacologic treatment options for neonatal seizures have expanded over the past 2
decades, and there is no consensus on optimal treatment strategy. We systematically …
decades, and there is no consensus on optimal treatment strategy. We systematically …
[HTML][HTML] Recommendations for the design of therapeutic trials for neonatal seizures
Although seizures have a higher incidence in neonates than any other age group and are
associated with significant mortality and neurodevelopmental disability, treatment is largely …
associated with significant mortality and neurodevelopmental disability, treatment is largely …
[HTML][HTML] Treating the symptom or treating the disease in neonatal seizures: a systematic review of the literature
R Falsaperla, B Scalia, A Giugno, P Pavone… - Italian Journal of …, 2021 - Springer
Aim The existing treatment options for neonatal seizures have expanded over the last few
decades, but no consensus has been reached regarding the optimal therapeutic protocols …
decades, but no consensus has been reached regarding the optimal therapeutic protocols …
Recent advances in the diagnosis and treatment of neonatal seizures
D Samanta - Neuropediatrics, 2021 - thieme-connect.com
Seizures are the most common neurological emergency in the neonates, and this age group
has the highest incidence of seizures compared with any other period of life. The author …
has the highest incidence of seizures compared with any other period of life. The author …