Dynamics of DNA methylation pattern
CL Hsieh - Current opinion in genetics & development, 2000 - Elsevier
Methylation patterns are the result of de novo methylation, demethylation, and the
maintenance of existing methylation. Although the existence and identity of an active …
maintenance of existing methylation. Although the existence and identity of an active …
DNA methylation in mouse embryonic stem cells and development
Mammalian development is associated with considerable changes in global DNA
methylation levels at times of genomic reprogramming. Normal DNA methylation is essential …
methylation levels at times of genomic reprogramming. Normal DNA methylation is essential …
[HTML][HTML] DNA methylation and demethylation in mammals
Cell type-specific DNA methylation patterns are established during mammalian
development and maintained in adult somatic cells. Understanding how these patterns of 5 …
development and maintained in adult somatic cells. Understanding how these patterns of 5 …
Maintenance and regulation of DNA methylation patterns in mammals
Proper establishment and faithful maintenance of epigenetic information is crucial for the
correct development of complex organisms. For mammals, it is now accepted that DNA …
correct development of complex organisms. For mammals, it is now accepted that DNA …
New concepts in DNA methylation
A Jeltsch, RZ Jurkowska - Trends in biochemical sciences, 2014 - cell.com
The widely-cited model of maintenance of DNA methylation at CpG sites implies that DNA
methylation is introduced by the Dnmt3 de novo DNA methyltransferases during early …
methylation is introduced by the Dnmt3 de novo DNA methyltransferases during early …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …
methylation has numerous functions: it is implicated in the repression of transposons and …
Structure and function of eukaryotic DNA methyltransferases
T Chen, E Li - Current topics in developmental biology, 2004 - Elsevier
DNA methylation is a common epigenetic modification found in eukaryotic organisms
ranging from fungi to mammals. Over the past 15 years, a number of eukaryotic DNA …
ranging from fungi to mammals. Over the past 15 years, a number of eukaryotic DNA …
[HTML][HTML] DNA methylation and DNA methyltransferases
JR Edwards, O Yarychkivska, M Boulard… - Epigenetics & …, 2017 - Springer
The prevailing views as to the form, function, and regulation of genomic methylation patterns
have their origin many years in the past, at a time when the structure of the mammalian …
have their origin many years in the past, at a time when the structure of the mammalian …
Mitotic inheritance of DNA methylation: more than just copy and paste
X Ming, B Zhu, Y Li - Journal of Genetics and Genomics, 2021 - Elsevier
Decades of investigation on DNA methylation have led to deeper insights into its metabolic
mechanisms and biological functions. This understanding was fueled by the recent …
mechanisms and biological functions. This understanding was fueled by the recent …
Regulation and function of mammalian DNA methylation patterns: a genomic perspective
H Wu, J Tao, YE Sun - Briefings in Functional Genomics, 2012 - academic.oup.com
Mammalian DNA methyltransferases (DNMTs) establish and maintain genomic DNA
methylation patterns that are required for proper epigenetic regulation of gene expression …
methylation patterns that are required for proper epigenetic regulation of gene expression …