Rheumatoid arthritis (RA) is an inflammatory joint disorder characterized by synovial
proliferation and inflammation, with eventual joint destruction if inadequately treated …

Rheumatoid arthritis (RA) and osteoarthritis (OA) are the two most prevalent joint diseases.
A such, they are important causes of pain and disability in a substantial proportion of the …

Melatonin is the major secretory product of the pineal gland during the night and has
multiple activities including the regulation of circadian and seasonal rhythms, and …

The hormone melatonin has many properties, including antioxidant, anti‐inflammatory, and
immunomodulatory effects. Melatonin has been demonstrated to be beneficial in several …

Our perception of the function of the pineal gland and its hormone melatonin has attained a
new dimension during the last decade. Through melatonin, the pineal becomes a principal …

Osteoarthritis (OA), the most common arthritis worldwide, is a degenerative joint disease
characterized by progressive cartilage breakdown, subchondral remodeling, and synovial …

The study was conducted to investigate the abnormalities in early morning serum melatonin
among patients with Juvenile Rheumatoid Arthritis (JRA) and to outline its relation to …

Melatonin has been reported to regulate circadian rhythms and have anti‐inflammatory
characteristics in various inflammatory autoimmune diseases, but its effects in diseases …

The pineal neurohormone melatonin (MLT) has been widely shown to exert an
immunostimulatory and antiapoptotic role, mainly by acting on Th cells and on T and B cell …

The pineal neurohormone melatonin is widely recognized as exerting important
immunoenhancing effects that act on specific receptors in immunocompetent cells. This …