Dear Editor, the recent article “Delirium and sleep disturbances in COVID-19: a possible role
for melatonin in hospitalized patients?” is quite noteworthy [1]. Zambrelli et al., mentioned …

The pandemic dissemination of the SARS-CoV-2 led, on the one hand, to a worldwide effort
to develop mechanistic-based therapeutics and vaccines, and on the other hand, the …

High mortality rates in severe progression of COVID-19 are predominantly caused by
pulmonary failure due to high-grade airway inflammation. As investigations on the efficacy of …

A recent retrospective study has provided evidence that COVID-19 infection may be notably
less common in those using supplemental melatonin. It is suggested that this phenomenon …

The world faces an exceptional new public health concern caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), subsequently termed the coronavirus …

This trial aims to evaluate the effectiveness of adding melatonin to the treatment protocol of
hospitalized coronavirus disease 2019 (COVID‐19) patients. This was an open‐label …

Background Melatonin, zinc, and multivitamins are among most recommended supplements
in the fight against coronavirus disease 2019 (COVID-19). We aimed to examine the efficacy …

Viral infections can cause serious diseases which lead to significant morbidity and mortality
of patients. In most cases, effective therapeutic approaches are lacking. Melatonin (MEL), a …

The recent report of Lenze and colleagues (Lenze et al. 2020) indicates that the selective
serotonin reuptake inhibitor (SSRI) fluvoxamine might reduce the rate of clinical …

Data indicate that controlling inflammatory responses to COVID‐19 may be as important as
antiviral therapies or could be an important adjunctive approach. Melatonin possesses anti …