[HTML][HTML] Implications of genetic variation in the complement system in age-related macular degeneration
Age-related macular degeneration (AMD) is the main cause of vision loss among the elderly
in the Western world. While AMD is a multifactorial disease, the complement system was …
in the Western world. While AMD is a multifactorial disease, the complement system was …
The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited
DH Anderson, MJ Radeke, NB Gallo, EA Chapin… - Progress in retinal and …, 2010 - Elsevier
During the past ten years, dramatic advances have been made in unraveling the biological
bases of age-related macular degeneration (AMD), the most common cause of irreversible …
bases of age-related macular degeneration (AMD), the most common cause of irreversible …
[HTML][HTML] The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment
MJ Geerlings, EK de Jong, AI den Hollander - Molecular immunology, 2017 - Elsevier
Age-related macular degeneration (AMD) is a progressive retinal disease and the major
cause of irreversible vision loss in the elderly. Numerous studies have found both common …
cause of irreversible vision loss in the elderly. Numerous studies have found both common …
Complement, age-related macular degeneration and a vision of the future
KM Gehrs, JR Jackson, EN Brown… - Archives of …, 2010 - jamanetwork.com
Age-related macular degeneration (AMD) is one of the most well-characterized late-onset,
complex trait diseases. Remarkable advances in our understanding of the genetic and …
complex trait diseases. Remarkable advances in our understanding of the genetic and …
The complement system in age-related macular degeneration
Age-related macular degeneration (AMD) is a chronic and progressive degenerative
disease of the retina, which culminates in blindness and affects mainly the elderly …
disease of the retina, which culminates in blindness and affects mainly the elderly …
Complement Inhibitors in Age‐Related Macular Degeneration: A Potential Therapeutic Option
S Qin, N Dong, M Yang, J Wang… - Journal of …, 2021 - Wiley Online Library
Age‐related macular degeneration (AMD) is a multifactorial disease, which can culminate in
irreversible vision loss and blindness in elderly. Nowadays, there is a big gap between dry …
irreversible vision loss and blindness in elderly. Nowadays, there is a big gap between dry …
Complement in age-related macular degeneration: a focus on function
DT Bradley, PF Zipfel, AE Hughes - Eye, 2011 - nature.com
Age-related macular degeneration (AMD) is an inflammatory disease, which causes visual
impairment and blindness in older people. The proteins of the complement system are …
impairment and blindness in older people. The proteins of the complement system are …
[HTML][HTML] Age-related macular degeneration: complement in action
M van Lookeren Campagne, EC Strauss, BL Yaspan - Immunobiology, 2016 - Elsevier
The complement system plays a key role in host-defense against common pathogens but
must be tightly controlled to avoid inflammation and tissue damage. Polymorphisms in …
must be tightly controlled to avoid inflammation and tissue damage. Polymorphisms in …
Age‐related macular degeneration: A disease of extracellular complement amplification
Age‐related macular degeneration (AMD) is a major cause of vision impairment in the
Western World, and with the aging world population, its incidence is increasing. As of today …
Western World, and with the aging world population, its incidence is increasing. As of today …
AMD and the alternative complement pathway: genetics and functional implications
PL Tan, C Bowes Rickman, N Katsanis - Human genomics, 2016 - Springer
Age-related macular degeneration (AMD) is an ocular neurodegenerative disorder and is
the leading cause of legal blindness in Western societies, with a prevalence of up to 8 …
the leading cause of legal blindness in Western societies, with a prevalence of up to 8 …
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