Abnormal DNA methylation is an important epigenetic regulator involving tumorigenesis.
Deciphering cancer common and specific DNA methylation patterns is essential for us to …

Aberrant DNA methylation is considered to be one of the most common hallmarks of cancer.
Several recent advances in assessing the DNA methylome provide great promise for …

Abnormal DNA methylation is known as playing an important role in the tumorgenesis. It is
helpful for distinguishing the specificity of diagnosis and therapeutic targets for cancers …

Aberrant DNA methylation is an important mechanism that contributes to oncogenesis. Yet,
few algorithms exist that exploit this vast dataset to identify hypo-and hypermethylated genes …

The alteration of DNA methylation landscape is a key epigenetic event in cancer. As the
accumulation of large-scale genome-wide DNA methylation data from clinical samples, we …

Background DNA methylation is the major form of epigenetic modifications through which
the cell regulates the gene expression and silencing. There have been extensive studies on …

Cancer cells typically exhibit aberrant DNA methylation patterns that can drive malignant
transformation. Whether cancer cells are dependent on these abnormal epigenetic …

ABSTRACT DNA methylation status is closely associated with diverse diseases, and is
generally more stable than gene expression, thus abnormal DNA methylation could be …

The comparison of DNA methylation patterns across cancer types (pan-cancer methylome
analyses) has revealed distinct subgroups of tumors that share similar methylation patterns …

Aberrant DNA methylation plays an important role in cancer progression. However, no
resource has been available that comprehensively provides DNA methylation-based …