Testicular sperm extraction and intracytoplasmic sperm injection (TESE-ICSI) is a frequently
used therapeutic option in azoospermic males. Genetic imprinting is a mechanism of gene …

Imprinting errors have been described in spermatozoa from infertile patients with
oligozoospermia and azoospermia. However, little is known about methylation of imprinted …

Genetic imprinting is a mechanism of gene regulation by which only one of the parental
copies of a gene is expressed. This process is mediated by the methylation of DNA. As …

Male factor infertility has been associated with abnormal DNA methylation at imprinted
genes. Little information is available on the status of imprinting in the sperm of men with …

OBJECTIVE: To study the methylation imprinting marks of two oppositely imprinted genes,
H19 and MEST/PEG1, in human testicular spermatozoa from azoospermic patients with …

Disorders in genetic imprinting are discussed as potential genetic risk in assisted
reproduction technology (ART), where most of the natural selection mechanisms are …

Genomic imprinting marks in the male germ line are already established in the adult
germinal stem cell population. We studied the methylation patterns of H19 and MEST …

Imprinted genes are expressed either from the paternal or the maternal allele, because the
other allele has been silenced in the mother's or father's germline. Imprints are characterized …

Infertility affects up to 15% of reproductive‐aged couples worldwide, with male factor being
detected in 40%–50% of the cases. Proper sperm production is associated with the …

Background Altered sperm DNA methylation patterns of imprinted genes as well as certain
spermatogenesis-related genes has been proposed as a possible mechanism of male …