PURPOSE To evaluate the objective tumor response rate and safety profile of oxaliplatin
when administered to patients with previously untreated metastatic colorectal …

Oxaliplatin is a useful agent in combination with 5-fluorouracil/leucovorin for the treatment of
patients with metastatic carcinoma of the colon or rectum whose disease has recurred or …

Background: Oxaliplatin, a platinum compound, has been commonly used around the world
for treating advanced colorectal cancer. The generally recommended dose and schedule of …

For the past 40 years, the mainstay of chemotherapy against colorectal cancer has been 5-
fluorouracil (5-FU), often administered in recent years with folinic acid modulation …

Oxaliplatin-based chemotherapy is an effective first-line treatment option for patients with
metastatic colorectal cancer (mCRC), which, in combination with targeted therapies and a …

Oxaliplatin, a platinum-based chemotherapeutic agent with a 1, 2-diaminocyclohexane
(DACH) carrier ligand, has shown in vitro and in vivo efficacy against many tumor cell lines …

Oxaliplatin is a third-generation platinum compound that has shown a definite role in the
management of colorectal cancer (CRC). Oxaliplatin in combination with fluorouracil and …

Oxaliplatin is used primarily in the treatment of metastatic colorectal cancer. In this
minireview, we discuss potentially important biotransformation pathways in light of its short …

Following the introduction of cisplatin and the demonstration of its importance in the
treatment of testicular and ovarian cancer, there was a need to develop less toxic …

Oxaliplatin, a new third-generation platinum complex, is active in the treatment of colorectal
and advanced ovarian cancers, both as monotherapy and in combination therapy. It has …