DNA replication is essential for all life forms. Although the process is fundamentally
conserved in the three domains of life, bioinformatic, biochemical, structural, and genetic …

▪ Abstract Genome sequences of a number of archaea have revealed an apparent paradox
in the phylogenies of the bacteria, archaea, and eukarya, as well as an intriguing set of …

Whereas the process of DNA replication is fundamentally conserved in the three domains of
life, the archaeal system is closer to that of eukarya than bacteria. In the time since the …

The precise and timely duplication of the genome is essential for cellular life. It is achieved
by DNA replication, a complex process that is conserved among the three domains of life …

The archaeal DNA replication machinery bears striking similarity to that of eukaryotes and is
clearly distinct from the bacterial apparatus. In recent years, considerable advances have …

It is now well recognized that the information processing machineries of archaea are far
more closely related to those of eukaryotes than to those of their prokaryotic cousins, the …

DNA replication is arguably the most fundamental biological process. On account of their
shared evolutionary ancestry, the replication machinery found in archaea is similar to that …

Recent advances in the characterization of the archaeal DNA replication system together
with comparative genomic analysis have led to the identification of several previously …

The analysis of completed archaeal genome sequences led to the identification of a set of
approximately 10–20 genes whose protein products were inferred to be involved in …

Since the first archaeal genome was sequenced, much attention has been focused on the
study of these unique microorganisms. We have learnt that although archaeal DNA …