DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
In the mammalian genome, DNA methylation is an epigenetic mechanism involving the
transfer of a methyl group onto the C5 position of the cytosine to form 5-methylcytosine. DNA …

[HTML][HTML] The role of activity-dependent DNA demethylation in the adult brain and in neurological disorders

G Bayraktar, MR Kreutz - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Over the last decade, an increasing number of reports underscored the importance of
epigenetic regulations in brain plasticity. Epigenetic elements such as readers, writers and …

The role of DNA methylation in the central nervous system and neuropsychiatric disorders

J Feng, G Fan - International review of neurobiology, 2009 - Elsevier
DNA methylation is an epigenetic mechanism in which the methyl group is covalently
coupled to the C5 position of the cytosine residue of CpG dinucleotides. DNA methylation …

The emerging role of DNA methylation in epileptogenesis

K Kobow, I Blümcke - Epilepsia, 2012 - Wiley Online Library
DNA methylation is a covalent chromatin modification, characterized by the biochemical
addition of a methyl group (‐CH3) to cytosine nucleotides via a DNA methyltransferase …

DNA methylation: a promising approach in management of Alzheimer's disease and other neurodegenerative disorders

G Kaur, SSS Rathod, MM Ghoneim, S Alshehri… - Biology, 2022 - mdpi.com
Simple Summary DNA methylation is an epigenetic modification of genes which affects
corresponding gene expression. During the developmental stage, embryonic stem cells …

DNA methylation and adult neurogenesis

EM Jobe, X Zhao - Brain Plasticity, 2017 - content.iospress.com
The role of DNA methylation in brain development is an intense area of research because
the brain has particularly high levels of CpG and mutations in many of the proteins involved …

DNA methylation and psychiatric disorders

C Liu, C Jiao, K Wang, N Yuan - Progress in molecular biology and …, 2018 - Elsevier
DNA methylation has been an important area of research in the study of molecular
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …

Role of DNA methylation and the DNA methyltransferases in learning and memory

MJ Morris, LM Monteggia - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Dynamic regulation of chromatin structure in postmitotic neurons plays an important role in
learning and memory. Methylation of cytosine nucleotides has historically been considered …

Evolution of DNA methylation in the human brain

H Jeong, I Mendizabal, S Berto, P Chatterjee… - Nature …, 2021 - nature.com
DNA methylation is a critical regulatory mechanism implicated in development, learning,
memory, and disease in the human brain. Here we have elucidated DNA methylation …

Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns

C Marchal, B Miotto - Journal of cellular physiology, 2015 - Wiley Online Library
DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …