[HTML][HTML] Genetic architecture of autism spectrum disorder: Lessons from large-scale genomic studies

L Choi, JY An - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a strong genetic
component. Recently developed genomic technologies, including microarray and next …

Genetics of autism spectrum disorder

G Ramaswami, DH Geschwind - Handbook of clinical neurology, 2018 - Elsevier
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized
by impaired social interaction and stereotyped behaviors. ASD has a strong and complex …

Genetic architecture in autism spectrum disorder

B Devlin, SW Scherer - Current opinion in genetics & development, 2012 - Elsevier
Autism spectrum disorder (ASD) is characterized by impairments in reciprocal social
interaction and communication, and by restricted and repetitive behaviors. Family studies …

Genes associated with autism spectrum disorder

X Li, H Zou, WT Brown - Brain research bulletin, 2012 - Elsevier
Autism spectrum disorder (ASD) is a heterogeneous grouping of neurodevelopmental
disorders characterized by impairment in social interaction, verbal communication and …

Genetics and genomics of autism spectrum disorder: embracing complexity

S De Rubeis, JD Buxbaum - Human molecular genetics, 2015 - academic.oup.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication and social interaction and the presence of repetitive …

Autism spectrum disorders: from genes to neurobiology

AJ Willsey, MW State - Current opinion in neurobiology, 2015 - Elsevier
Highlights•High throughput genomic methods are rapidly increasing the pool of ASD
genes.•Heterogeneity, pleiotropy, and brain complexity complicate translation to …

Genetic research in autism spectrum disorders

EB Robinson, BM Neale, SE Hyman - Current opinion in pediatrics, 2015 - journals.lww.com
Genetic studies have the potential to identify the biological underpinnings of ASDs and other
neuropsychiatric disorders. The data they generate are already being used to examine …

Genetic heterogeneity in autism: From single gene to a pathway perspective

JY An, C Claudianos - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
The extreme genetic heterogeneity of autism spectrum disorder (ASD) represents a major
challenge. Recent advances in genetic screening and systems biology approaches have …

Progress in the genetics of autism spectrum disorder

M Woodbury‐Smith, SW Scherer - Developmental Medicine & …, 2018 - Wiley Online Library
A genetic basis for autism spectrum disorder (ASD) is now well established, and with the
availability of high‐throughput microarray and sequencing platforms, major advances have …

Autism spectrum disorder genetics: diverse genes with diverse clinical outcomes

ME Talkowski, EV Minikel… - Harvard review of …, 2014 - journals.lww.com
The last several years have seen unprecedented advances in deciphering the genetic
etiology of autism spectrum disorders (ASDs). Heritability studies have repeatedly affirmed a …