The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction

DC McFadden, M De Jesus, A Casadevall - Journal of Biological Chemistry, 2006 - ASBMB
The most distinctive feature of the human pathogenic fungus is a polysaccharide capsule
that is essential for virulence and is composed primarily of glucuronoxylomannan (GXM) and …

Elucidating the Immunological Function of the Cryptococcus Neoformans Capsule

A Vecchiarelli, E Pericolini, E Gabrielli… - Future …, 2013 - Taylor & Francis
The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent
of life-threatening infections in immunocompromised subjects. A unique characteristic of …

Capsule Structural Heterogeneity and Antigenic Variation in Cryptococcus neoformans

DC McFadden, BC Fries, F Wang, A Casadevall - Eukaryotic Cell, 2007 - Am Soc Microbiol
Cryptococcus neoformans is a human pathogenic fungus with a capsule composed primarily
of glucuronoxylomannan (GXM) that is important for virulence. Current views of GXM …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Immunomodulatory Role of Capsular Polysaccharides Constituents of Cryptococcus neoformans

D Decote-Ricardo, IF LaRocque-de-Freitas… - Frontiers in …, 2019 - frontiersin.org
Cryptococcosis is a systemic fungal infection caused by Cryptococcus neoformans. In
immunocompetent patients, cryptococcal infection is often confined to the lungs. In …

Isolation of the Third Capsule-Associated Gene,CAP60, Required for Virulence in Cryptococcus neoformans

YC Chang, KJ Kwon-Chung - Infection and immunity, 1998 - Am Soc Microbiol
ABSTRACT A polysaccharide capsule is one of the most important virulence factors for the
pathogenic fungus Cryptococcus neoformans. We previously characterized two capsule …

Radiological Studies Reveal Radial Differences in the Architecture of the Polysaccharide Capsule of Cryptococcus neoformans

RA Bryan, O Zaragoza, T Zhang, G Ortiz… - Eukaryotic …, 2005 - Am Soc Microbiol
The polysaccharide capsule of the pathogenic fungus Cryptococcus neoformans is an
important virulence factor, but relatively little is known about its architecture. We applied a …

The polysaccharide capsule of the pathogenic fungus Cryptococcus neoformans enlarges by distal growth and is rearranged during budding

O Zaragoza, A Telzak, RA Bryan… - Molecular …, 2006 - Wiley Online Library
The capsule of Cryptococcus neoformans can undergo dramatic enlargement, a
phenomenon associated with virulence. A prior study that used Ab to the capsule as a …