The effects of capsular polysaccharides, galactoxylomannan (GalXM) and
glucuronoxylomannan (GXM), from acapsular (GXM negative) and encapsulate strains of …

Glucuronoxylomannan (GXM), the major capsular component in the Cryptococcus complex,
interacts with the immune system in multiple ways, which include the activation of Toll-like …

Isolated nonhydrolyzed cryptococcal polysaccharide is a rather specific potent inhibitor of
the phagocytosis of Cryptococcus neoformans by human leukocytes in vitro. When an …

Few fungi are pathogenic to humans. Of these, Cryptococcus neoformans has emerged as
an important cause of mortality in immunocompromised patients, especially those with AIDS …

Infections with the encapsulated fungus Cryptococcus neoformans are usually acquired via
inhalation, and the presence of a capsule has been identified as a virulence factor …

Monoclonal antibodies (MAbs) to the capsular polysaccharide of the pathogenic fungus
Cryptococcus neoformans can prolong survival and decrease organ fungal burden in …

Immunoglobulin G1 (IgG1) monoclonal antibodies (MAbs) to the capsular
glucuronoxylomannan (GXM) were studied for their ability to modify the course of …

Cryptococcus neoformans is variably encapsulated in vitro, whereas in tissues it develops a
large capsule. We observed that cells of a strain with thin capsules, when growing in a …

Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

The human pathogenic fungus Cryptococcus neoformans has a distinctive polysaccharide
(PS) capsule that enlarges during infection. The capsule is essential for virulence, but the …