Me CP 2 is a chromatin‐associated protein that is mutated in Rett syndrome. Its methyl‐CpG‐
binding domain interacts with DNA containing methylated cytosine, but other modes of …

Two new studies reveal novel DNA-binding properties of MeCP2, mutations of which cause
Rett syndrome. Baker et al. report critical roles for the AT-hook domain of MeCP2 in …

hMeCP2 (human methylated DNA-binding protein 2), mutations of which cause most cases
of Rett syndrome (RTT), is involved in the transmission of repressive epigenetic signals …

Sporadic mutations in the hMeCP2 gene, coding for a protein that preferentially binds
symmetrically methylated CpGs, result in the severe neurological disorder Rett syndrome …

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder associated with
intellectual disabilities, which almost exclusively affects females during early childhood with …

Rett syndrome is a neurological, X chromosomal-linked disorder associated with mutations
in the MECP2 gene. MeCP2 protein has been proposed to play a role in transcriptional …

Mutations of the methylated DNA binding protein MeCP2, a multifunctional protein that is
thought to transmit epigenetic information encoded as methylated CpG dinucleotides to the …

Abstract Methylated CpG Binding Protein 2 (MeCP2) is a nuclear protein named for its ability
to selectively recognize methylated DNA. Much attention has been focused on …

Abstract Methyl CpG-binding protein 2 (MeCP2), the mutated protein in Rett syndrome
(RTT), is a crucial chromatin-modifying and gene-regulatory protein that has two main …

The methyl-CpG-binding protein 2 (MECP2) serves both organizational and transcriptional
functions in the nucleus, with two well-characterized domains integrally related to these …