Glioblastoma (GBM) is a highly aggressive and lethal type of brain tumor with complex and
diverse molecular signaling pathways involved that are in its development and progression …

As primary intracranial tumors of the central nervous system (CNS), gliomas pose formidable
challenges in the field of oncology due to their aggressiveness, poor prognosis, high risk of …

Glioblastoma (GBM), a highly aggressive form of brain cancer, is considered one of the
deadliest cancers, and even with the most advanced medical treatments, most affected …

Glioblastoma is one of the most aggressive central nervous system malignancies with high
morbidity and mortality. Current clinical approaches, including surgical resection …

Cancer patients suffer from the toxicity of chemotherapy. Antidote, given as a remedy limiting
poison, is an effective way to counteract toxicity. However, few antidotes abrogate …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Glioblastoma Multiforme (GBM) is a devastating disease with a low survival rate and few
efficacious treatment options. The fast growth, late diagnostics, and off-target toxicity of …

Even though substantial advances in understanding glioma pathogenesis have prompted a
more rational design of potential therapeutic strategies, glioblastoma multiforme remains an …

Diagnosing and treating glioblastoma patients is currently hindered by several obstacles,
such as tumor heterogeneity, the blood-brain barrier, tumor complexity, drug efflux pumps …

Simple Summary Glioblastoma multiforme (GBM) are among the most lethal tumors. The
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …